Cystatin C in macular and neuronal degenerations: implications for mechanism(s) of age-related macular degeneration (Q43241222)

17 November 2017

Cystatin C in macular and neuronal degenerations: implications for mechanism(s) of age-related macular degeneration (English)

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17 November 2017

1

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17 November 2017

Paul Hiscott

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PubMed ID

19917302

17 November 2017

Christine Gosden

series ordinal

3

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PubMed ID

19917302

17 November 2017

Ian Grierson

series ordinal

4

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17 November 2017

14 November 2009

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17 November 2017

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17 November 2017

50

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17 November 2017

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17 November 2017

737-742

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The human cystatin C gene (CST3), mutated in hereditary cystatin C amyloid angiopathy, is located on chromosome 20.

17 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Structure and expression of the human cystatin C gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Protein inhibitors of proteinases from brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Inhibition of mammalian legumain by some cystatins is due to a novel second reactive site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

SstII polymorphic sites in the promoter region of the human cystatin C gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Expression of the cysteine proteinase inhibitor cystatin C mRNA in rat eye

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Alzheimer's disease and the cystatin C gene polymorphism: an association study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

The importance of the second hairpin loop of cystatin C for proteinase binding. Characterization of the interaction of Trp-106 variants of the inhibitor with cysteine proteinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Human cystatin, a new protein inhibitor of cysteine proteinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C as a risk factor for Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Post- -globulin: isolation and physicochemical characterization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for beta 2-microglobulin in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin mRNA is expressed by the ciliary epithelium of the chick eye

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Conformational Variability of Chicken Cystatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Importance of the evolutionarily conserved glycine residue in the N-terminal region of human cystatin C (Gly-11) for cysteine endopeptidase inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Domain swapping in N-truncated human cystatin C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C modulates cerebral beta-amyloidosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Codeposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C in the human pancreas and gut: an immunohistochemical study of normal and neoplastic tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Characterization by rapid-kinetic and equilibrium methods of the interaction between N-terminally truncated forms of chicken cystatin and the cysteine proteinases papain and actinidin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Occurrence of gamma-trace in the calcitonin-producing C-cells of simian thyroid gland and human medullary thyroid carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Quantitation of gamma-trace in human biological fluids: indications for production in the central nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Two-step mechanism of inhibition of cathepsin B by cystatin C due to displacement of the proteinase occluding loop

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Focus on molecules: cystatin C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Fate of cystatin C lacking the leader sequence in RPE cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Analysis of expressed sequence tags of retinal pigment epithelium: cystatin C is an abundant transcript.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Unexpected intracellular localization of the AMD-associated cystatin C variant.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Precursor cystatin C in cultured retinal pigment epithelium cells: evidence for processing through the secretory pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

The role of the Val57 amino-acid residue in the hinge loop of the human cystatin C. Conformational studies of the beta2-L1-beta3 segments of wild-type human cystatin C and its mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Protein analysis of monkey aqueous humor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiopathy (HCCAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

AceView: a comprehensive cDNA-supported gene and transcripts annotation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Sertoli cell and germ cell cystatin C: stage-dependent expression of two distinct messenger ribonucleic acid transcripts in rat testes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

The cystatins: Protein inhibitors of cysteine proteinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Protein Inhibitors of Cysteine Proteinases. III. Amino-Acid Sequence of Cystatin from Chicken Egg White

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Cystatin C in the anterior segment of rat and mouse eyes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Expression of cystatin C in rat, monkey and human brains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

CST3 genotype associated with exudative age related macular degeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

Demonstration of gamma-trace in normal endocrine cells of the adrenal medulla and in phaeochromocytoma. An immunohistochemical study in monkey, dog and man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VISRES.2009.10.022

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VISRES.2009.10.022

1 reference

17 November 2017

1 reference

PubMed ID

19917302