Introduction of a strong temperature-sensitive phenotype into enterovirus 71 by altering an amino acid of virus 3D polymerase (Q43244272)

17 November 2017

Introduction of a strong temperature-sensitive phenotype into enterovirus 71 by altering an amino acid of virus 3D polymerase (English)

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17 November 2017

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Jen-Ren Wang

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Su Ih-jen

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object named as

Ih-Jen Su

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author name string

Yen-Hua Kung

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17 November 2017

Sheng-Wen Huang

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17 November 2017

Pin-Hwa Kuo

3

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17 November 2017

David Kiang

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17 November 2017

Mei-Shang Ho

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17 November 2017

Ching-Chung Liu

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17 November 2017

Chun-Keung Yu

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17 November 2017

language of work or name

English

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publication date

10 November 2009

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17 November 2017

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17 November 2017

396

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17 November 2017

1-9

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17 November 2017

1

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A point mutation in the poliovirus polymerase gene determines a complementable temperature-sensitive defect of RNA replication

17 November 2017

1 reference

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Mutations in the poliovirus P1 capsid precursor at arginine residues VP4-ARG34, VP3-ARG223, and VP1-ARG129 affect virus assembly and encapsidation of genomic RNA.

7 January 2021

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A sequence motif in many polymerases

7 January 2021

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Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys.

7 January 2021

1 reference

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Quantitative analysis of poliomyelitis-like paralysis in mice induced by a poliovirus replicon.

7 January 2021

1 reference

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Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model

7 January 2021

1 reference

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IN VITRO SYNTHESIS OF VIRAL RNA BY THE POLIOVIRUS RNA POLYMERASE

7 January 2021

1 reference

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Poliovirus protease 3C(pro) kills cells by apoptosis.

7 January 2021

1 reference

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Regulation of picornavirus gene expression

7 January 2021

1 reference

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Cytokine production in motor neurons by poliovirus replicon vector gene delivery

7 January 2021

1 reference

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Risk Factors of Enterovirus 71 Infection and Associated Hand, Foot, and Mouth Disease/Herpangina in Children During an Epidemic in Taiwan

7 January 2021

1 reference

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Retrograde axonal transport: a major transmission route of enterovirus 71 in mice

7 January 2021

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The molecular basis of mouse adaptation by human enterovirus 71.

7 January 2021

1 reference

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An attempt to unify the structure of polymerases

7 January 2021

1 reference

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Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A)

7 January 2021

1 reference

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An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group.

7 January 2021

1 reference

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Importance of arginine 20 of the swine vesicular disease virus 2A protease for activity and virulence

7 January 2021

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Inherent instability of poliovirus genomes containing two internal ribosome entry site (IRES) elements supports a role for the IRES in encapsidation

7 January 2021

1 reference

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Poliovirus protein 3CD is the active protease for processing of the precursor protein P1 in vitro

7 January 2021

1 reference

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Poliovirus tropism and attenuation are determined after internal ribosome entry

7 January 2021

1 reference

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Genomic regions of coxsackievirus B3 associated with cardiovirulence

7 January 2021

2 references

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7 January 2021

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7 January 2021

Enterovirus 71 outbreaks, Taiwan: occurrence and recognition

1 reference

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Evolution of EV71 genogroup in Taiwan from 1998 to 2005: An emerging of subgenogroup C4 of EV71

7 January 2021

1 reference

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Incidence and case-fatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan

7 January 2021

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Yellow fever virus replicons as an expression system for hepatitis C virus structural proteins

7 January 2021

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

7 January 2021

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Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure

7 January 2021

1 reference

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Protein-primed RNA synthesis by purified poliovirus RNA polymerase

7 January 2021

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Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice

7 January 2021

1 reference

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Immunization of mice with poliovirus replicons expressing the C-fragment of tetanus toxin protects against lethal challenge with tetanus toxin

7 January 2021

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Demonstration of the specificity of poliovirus encapsidation using a novel replicon which encodes enzymatically active firefly luciferase

7 January 2021

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RNA-dependent RNA polymerase consensus sequence of the L-A double-stranded RNA virus: definition of essential domains

7 January 2021

1 reference

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Mutations at KFRDI and VGK domains of enterovirus 71 3C protease affect its RNA binding and proteolytic activities

7 January 2021

1 reference

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A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection

7 January 2021

1 reference

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The interaction of cytoplasmic RNA viruses with the nucleus

7 January 2021

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An infectious clone of the West Nile flavivirus

7 January 2021

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Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein

7 January 2021

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Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor

7 January 2021

1 reference

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Effects of mutations in poliovirus 3Dpol on RNA polymerase activity and on polyprotein cleavage

7 January 2021

1 reference

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Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis

7 January 2021

1 reference

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7 January 2021

Mapping the genetic determinants of pathogenicity and plaque phenotype in swine vesicular disease virus

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7 January 2021

Construction and characterization of poliovirus subgenomic replicons

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7 January 2021

Analysis of RNA synthesis of type 1 poliovirus by using an in vitro molecular genetic approach

1 reference

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7 January 2021

10.1016/J.VIROL.2009.10.017

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DOI

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release_qz3v5e2ew5dfbhuzw5htrhuw4a

17 November 2017

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https://api.fatcat.wiki/v0/release/qz3v5e2ew5dfbhuzw5htrhuw4a

24 November 2022

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