Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. (Q43254531)

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7 December 2019

title

Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population (English)

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6

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Dominique Turck

11

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Jean-Frédéric Colombel

10

object named as

Colombel JF

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author name string

Spire-Vayron de la Moureyre C

1

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Debuysere H

2

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Mastain B

3

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Vinner E

4

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Marez D

5

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Chevalier D

7

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Brique S

8

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Motte K

9

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Noel C

12

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Flipo RM

13

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Pol A

14

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Lhermitte M

15

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Lafitte JJ

16

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Libersa C

17

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Broly F

18

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language of work or name

English

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publication date

1 October 1998

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British Journal of Pharmacology

7 December 2019

published in

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volume

125

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issue

4

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page(s)

879-887

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Thiopurine methyltransferase activity in a French population: h.p.l.c. assay conditions and effects of drugs and inhibitors

7 December 2019

cites work

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Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations

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Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

21 January 2018

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Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6‐mercaptopurine and azathioprine

21 January 2018

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Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

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Pharmacokinetics, dose adjustments, and 6-mercaptopurine/methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency

21 January 2018

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Possibilities for therapeutic drug monitoring of azathioprine: 6-thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells

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The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients

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7 January 2021

Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

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7 January 2021

Thiopurine methyltransferase activity in a sample population of black subjects in Florida

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7 January 2021

Erythrocyte fraction affects red blood cell thiopurine methyltransferase activity

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7 January 2021

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

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7 January 2021

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms

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7 January 2021

Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia

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7 January 2021

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

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7 January 2021

Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults

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7 January 2021

Thiopurine methyltransferase activity in American white subjects and black subjects

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7 January 2021

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.

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7 January 2021

Monitoring of azathioprine-induced immunosuppression with thiopurine methyltransferase activity in kidney transplant recipients

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7 January 2021

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

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7 January 2021

Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity

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7 January 2021

Thiopurine Methyltransferase in Humans: Development and Tissue Distribution

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7 January 2021

Thiopurine methyltransferase activity in a Korean population sample of children.

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7 January 2021

Thiol S-methylation in uremia: erythrocyte enzyme activities and plasma inhibitors

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7 January 2021

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient

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7 January 2021

Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis

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7 January 2021

Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism

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7 January 2021

Segregation analysis of human red blood cell thiopurine methyltransferase activity

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7 January 2021

Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

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7 January 2021

Identifiers

DOI

10.1038/SJ.BJP.0702152

1 reference

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7 December 2019

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7 December 2019

PubMed publication ID

9831928

1 reference

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