Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites (Q43264628)

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scientific article published in August 2000

Language	Label	Description	Also known as
English	Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites	scientific article published in August 2000

Statements

scholarly article

1 reference

Europe PubMed Central

17 November 2017

Disparate ligand-mediated Ca(2+) responses by wild-type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites (English)

1 reference

Europe PubMed Central

17 November 2017

author name string

P J Pauwels

1

1 reference

Europe PubMed Central

17 November 2017

F C Colpaert

2

1 reference

Europe PubMed Central

17 November 2017

language of work or name

0 references

publication date

1 August 2000

1 reference

Europe PubMed Central

17 November 2017

British Journal of Pharmacology

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Europe PubMed Central

17 November 2017

130

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Europe PubMed Central

17 November 2017

1505-1512

1 reference

Europe PubMed Central

17 November 2017

7

1 reference

Europe PubMed Central

17 November 2017

Adrenergic Receptors From Molecular Structure to in vivo function

1 reference

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25 May 2018

G-protein activation by putative antagonists at mutant Thr373Lys alpha2A adrenergic receptors

1 reference

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Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor

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Gene targeting--homing in on alpha 2-adrenoceptor-subtype function

1 reference

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25 May 2018

Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system

1 reference

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Receptors linked to inhibition of adenylate cyclase: additional signaling mechanisms

1 reference

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Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation

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Structural basis of beta-adrenergic receptor function.

1 reference

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Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells

1 reference

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25 May 2018

Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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The effect of site-directed mutagenesis of two transmembrane serine residues on agonist-specific coupling of a cloned human alpha2A-adrenoceptor to adenylyl cyclase

1 reference

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Agonist efficacy at the alpha2A-adrenoceptor:G alpha15 fusion protein: an analysis based on Ca2+ responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10928951

12 December 2020

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The unique nature of the serine interactions for alpha 1-adrenergic receptor agonist binding and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10928951

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Heterogeneous ligand-mediated Ca(++) responses at wt and mutant alpha(2A)-adrenoceptors suggest multiple ligand activation binding sites at the alpha(2A)-adrenoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10928951

12 December 2020

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Ligand- and subtype-selective coupling of human alpha-2 adrenoceptors to Ca++ elevation in Chinese hamster ovary cells

1 reference

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Chloroethylclonidine and 2-Aminoethyl Methanethiosulfonate Recognize Two Different Conformations of the Human α2A-Adrenergic Receptor

1 reference

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Ligand-receptor interactions as controlled by wild-type and mutant Thr(370)Lys alpha2B-adrenoceptor-Galpha15 fusion proteins

1 reference

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12 December 2020

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Alpha 2-C10 adrenergic receptors expressed in rat 1 fibroblasts can regulate both adenylylcyclase and phospholipase D-mediated hydrolysis of phosphatidylcholine by interacting with pertussis toxin-sensitive guanine nucleotide-binding proteins

1 reference

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Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs

1 reference

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Identifiers

10.1038/SJ.BJP.0703455

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

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