Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations (Q43265231)

17 November 2017

title

Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations (English)

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17 November 2017

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Stéphane Téletchéa

1

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17 November 2017

Tormod Skauge

series ordinal

2

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17 November 2017

Einar Sletten

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3

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17 November 2017

Jirí Kozelka

series ordinal

4

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17 November 2017

language of work or name

English

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publication date

1 November 2009

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Chemistry—A European Journal

17 November 2017

published in

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17 November 2017

volume

15

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17 November 2017

issue

45

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17 November 2017

page(s)

12320-12337

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describes a project that uses

17 November 2017

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Unrestrained 5 ns molecular dynamics simulation of a cisplatin-DNA 1,2-GG adduct provides a rationale for the NMR features and reveals increased conformational flexibility at the platinum binding site

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Molecular dynamic simulations of cisplatin- and oxaliplatin-d(GG) intrastand cross-links reveal differences in their conformational dynamics

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Fast interstrand cross-linking of cisplatin-DNA monoadducts compared with intrastrand chelation: a kinetic study using hairpin-stabilized duplex oligonucleotides

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

A d(GpG)-platinated decanucleotide duplex is kinked. An extended NMR and molecular mechanics study

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Resonance assignments of non-exchangeable protons in B type DNA oligomers, an overview

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Determination of sugar conformations by NMR in larger DNA duplexes using both dipolar and scalar data: application to d(CATGTGACGTCACATG)2.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Sequence-dependent variations in the 31P NMR spectra and backbone torsional angles of wild-type and mutant Lac operator fragments

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

The role of the phosphorus BI-BII transition in protein-DNA recognition: the NF-kappaB complex

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

BI-BII transitions in B-DNA.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Solution structure of the CpG containing d(CTTCGAAG)2 oligonucleotide: NMR data and energy calculations are compatible with a BI/BII equilibrium at CpG.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Flexibility of the B-DNA backbone: effects of local and neighbouring sequences on pyrimidine-purine steps

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Fixing the conformations of diamineplatinum(II)-GpG chelates: NMR and CD signatures of individual rotamers

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Nucleic acids and nuclear magnetic resonance

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Alpha/gamma transitions in the B-DNA backbone

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

A combined effect of molecular electrostatic potential and N7 accessibility explains sequence-dependent binding of cis-[Pt(NH3)2(H2O)2]2+ to DNA duplexes

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

A rare example of three abundant conformers in one retro model of the cisplatin-DNA d(GpG) intrastrand cross link. Unambiguous evidence that guanine O6 to carrier amine ligand hydrogen bonding is not important. possible effect of the Lippard base pa

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Chiral differentiation of DNA adducts formed by enantiomeric analogues of antitumor cisplatin is sequence-dependent

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Sensitivity of NMR internucleotide distances to B-DNA conformation: underlying mechanics

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Operator recognition by the phage 434 cI repressor: MD simulations of free and bound 50-bp DNA reveal important differences between the OR1 and OR2 sites

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

DNA Sequence Context and Protein Composition Modulate HMG-Domain Protein Recognition of Cisplatin-Modified DNA

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

Platination of the (T2G4)4 telomeric sequence: a structural and cross-linking study.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

31P NMR analysis of the DNA conformation induced by protein binding

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.200901158

21 January 2018

Identifiers

DOI

10.1002/CHEM.200901158

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17 November 2017

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