The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone. (Q43272225)

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8 February 2020

title

The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone (English)

1 reference

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8 February 2020

1 reference

amiodarone

15 June 2024

Jakob Gierten

1

1 reference

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8 February 2020

Eckhard Ficker

2

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8 February 2020

Ramona Bloehs

3

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8 February 2020

Patrick A Schweizer

4

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8 February 2020

Edgar Zitron

5

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8 February 2020

Christoph Karle

7

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8 February 2020

Dierk Thomas

9

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8 February 2020

publication date

24 September 2009

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Naunyn-Schmiedeberg's Archives of Pharmacology

8 February 2020

published in

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8 February 2020

volume

381

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8 February 2020

issue

3

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8 February 2020

page(s)

261-270

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Background potassium current active during the plateau of the action potential in guinea pig ventricular myocytes

8 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00210-009-0454-4

Amiodarone-associated proarrhythmic effects. A review with special reference to torsade de pointes tachycardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-009-0454-4

Amiodarone: reevaluation of an old drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-009-0454-4

Plasma protein binding of amiodarone in a patient population: measurement by erythrocyte partitioning and a novel glass-binding method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-009-0454-4

The acid-sensitive potassium channel TASK-1 in rat cardiac muscle.

21 January 2018

1 reference

12 December 2020

Activation of protein kinase C epsilon inhibits the two-pore domain K+ channel, TASK-1, inducing repolarization abnormalities in cardiac ventricular myocytes

1 reference

12 December 2020

Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel

1 reference

12 December 2020

An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum

1 reference

12 December 2020

TASK, a human background K+ channel to sense external pH variations near physiological pH

1 reference

12 December 2020

Cardiac channelopathies

1 reference

12 December 2020

The novel antiarrhythmic drug dronedarone: comparison with amiodarone

1 reference

12 December 2020

Inhibition of calmodulin and protein kinase C by amiodarone and other class III antiarrhythmic agents

1 reference

12 December 2020

Amiodarone for atrial fibrillation

1 reference

12 December 2020

Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3

1 reference

12 December 2020

Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein

1 reference

12 December 2020

Amiodarone: clinical trials

1 reference

12 December 2020

Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium

1 reference

12 December 2020

An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.

1 reference

12 December 2020

Molecular physiology of cardiac repolarization

1 reference

12 December 2020

The TASK family: two-pore domain background K+ channels

1 reference

12 December 2020

Clinical pharmacokinetics of amiodarone

1 reference

12 December 2020

Efficacy and safety of long-term amiodarone in treatment of cardiac arrhythmias: dosage experience

1 reference

12 December 2020

Properties and modulation of mammalian 2P domain K+ channels.

1 reference

12 December 2020

The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.

1 reference

12 December 2020

Block of the background K(+) channel TASK-1 contributes to arrhythmogenic effects of platelet-activating factor

1 reference

12 December 2020

Effect of amiodarone on cytokine release and on enzyme activities of mouse alveolar macrophages, bone marrow macrophages, and blood monocytes

1 reference

12 December 2020

Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels

1 reference

12 December 2020

Local anesthetic inhibition of baseline potassium channels with two pore domains in tandem

1 reference

12 December 2020

The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.

1 reference

12 December 2020

Potassium leak channels and the KCNK family of two-P-domain subunits

1 reference

12 December 2020

Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A.

1 reference

12 December 2020