Combined administration of an mGlu2/3 receptor agonist and a 5-HT 2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants (Q43286008)

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scientific article published on 26 August 2009

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English	Combined administration of an mGlu2/3 receptor agonist and a 5-HT 2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants	scientific article published on 26 August 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Combined administration of an mGlu2/3 receptor agonist and a 5-HT 2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

author name string

Jason M Uslaner

1

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Sean M Smith

2

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Sarah L Huszar

3

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Rashida Pachmerhiwala

4

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Europe PubMed Central

PubMed publication ID

18 November 2017

Richard M Hinchliffe

5

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Joshua D Vardigan

6

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Europe PubMed Central

PubMed publication ID

18 November 2017

Pete H Hutson

7

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PubMed publication ID

18 November 2017

publication date

26 August 2009

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PubMed publication ID

18 November 2017

Psychopharmacology

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PubMed publication ID

18 November 2017

206

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Europe PubMed Central

PubMed publication ID

18 November 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

641-651

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Europe PubMed Central

PubMed publication ID

18 November 2017

Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine

1 reference

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Effects of ritanserin on sleep disturbances of dysthymic patients

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https://pubmed.ncbi.nlm.nih.gov/19707745

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Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex

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https://pubmed.ncbi.nlm.nih.gov/19707745

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Tolerance to the motor impairment, but not to the reversal of PCP-induced motor activities by oral administration of the mGlu2/3 receptor agonist, LY379268

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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The ratios of serotonin2 and dopamine2 affinities differentiate atypical and typical antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Enhancement of antipsychoticlike properties of raclopride in rats using the selective serotonin2A receptor antagonist MDL 100,907.

1 reference

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Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0.]hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidine-induced behaviors in monoamine-depleted rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Place and matching-to-place spatial learning affected by rat inbreeding (Dark-Agouti, Fischer 344) and albinism (Wistar, Sprague-Dawley) but not domestication (wild rat vs. Long-Evans, Fischer-Norway).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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A role for noradrenergic transmission in the actions of phencyclidine and the antipsychotic and antistress effects of mGlu2/3 receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential actions of typical and atypical antipsychotic drugs on dopamine release in the core and shell of the nucleus accumbens

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

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Subchronic effects of the GABA-agonist lorazepam and the 5-HT2A/2C antagonist ritanserin on driving performance, slow wave sleep and daytime sleepiness in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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Blockade by pimozide of (+)-amphetamine-induced hyperkinesia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

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Anxiolytic-like profile in Wistar, but not Sprague-Dawley rats in the social interaction test.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in visual acuity within pigmented, and between pigmented and albino rat strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of L-dopa and (+)-amphetamine on the locomotor activity after pimozide and phenoxybenzamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of tyrosine hydroxylase and dopamine-beta-hydroxylase inhibition with the effects of various 6-hydroxydopamine treatments on d-amphetamine induced motor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1- and alpha 2-adrenoreceptor antagonists differentially influence locomotor and stereotyped behaviour induced by d-amphetamine and apomorphine in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

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based on heuristic

inferred from PubMed ID database lookup

Role of dopaminergic system in core part of nucleus accumbens in hyperlocomotion and rearing induced by MK-801 in rats: a behavioral and in vivo microdialysis study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional effects of MK-801 on dopamine release: effects of competitive NMDA or 5-HT2A receptor blockade.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu2/3 receptor agonist LY379268 blocks the expression of locomotor sensitization by amphetamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blunted brain metabolic response to ketamine in mice lacking D(1A) dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism at 5-HT(2A) receptors potentiates the effect of haloperidol in a conditioned avoidance response task in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiamphetamine effects following inhibition of tyrosine hydroxylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of L-alpha-methyltyrosine, an inhibitor of tyrosine hydroxylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of alpha-methyltyrosine on brain catecholamine levels and on spontaneous and amphetamine-stimulated motor activity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizophrenia drug says goodbye to dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of action of atypical neuroleptics in relation to the phencyclidine model of schizophrenia: role of 5-HT2 receptor and alpha 1-adrenoceptor antagonism [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19707745

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-009-1644-Y

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

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