Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity. (Q43290384)

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scientific article published on 18 August 2009

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English	Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity.	scientific article published on 18 August 2009

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scholarly article

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Europe PubMed Central

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5 February 2020

Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity (English)

1 reference

Europe PubMed Central

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5 February 2020

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inferred from title

insulin resistance

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2

1 reference

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5 February 2020

author name string

S Beck Jørgensen

1

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5 February 2020

K Hewitt

3

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5 February 2020

B E Kemp

4

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5 February 2020

G R Steinberg

5

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5 February 2020

publication date

18 August 2009

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5 February 2020

1 reference

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5 February 2020

52

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5 February 2020

2395-2404

1 reference

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11

1 reference

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5 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-009-1483-8

0 references

PKC-theta knockout mice are protected from fat-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1483-8

21 January 2018

Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1483-8

21 January 2018

A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for JNK in obesity and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disordered lipid metabolism and the pathogenesis of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonyl-CoA, fuel sensing, and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

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Inflammation and metabolic disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase-dependent pathway that is impaired with obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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