Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance (Q43435087)

23 November 2017

Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance (English)

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23 November 2017

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Peixiang Lan

1

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23 November 2017

Cai Zhang

2

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23 November 2017

Qiuju Han

3

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23 November 2017

Jian Zhang

4

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23 November 2017

Zhigang Tian

5

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23 November 2017

language of work or name

English

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publication date

23 May 2013

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23 November 2017

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23 November 2017

58

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23 November 2017

1

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73-85

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Risk factors for hepatocellular carcinoma in a cohort infected with hepatitis B or C.

23 November 2017

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Control of hepatitis B virus replication by innate response of HepaRG cells.

21 January 2018

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CD8(+) T cell control of hepatitis B virus replication: direct comparison between cytolytic and noncytolytic functions.

21 January 2018

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Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon

21 January 2018

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Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

21 January 2018

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The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

21 January 2018

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Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

21 January 2018

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An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection

21 January 2018

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Reversal of hepatitis B virus-induced immune tolerance by an immunostimulatory 3p-HBx-siRNAs in a retinoic acid inducible gene I-dependent manner

21 January 2018

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5' Triphosphorylated small interfering RNAs control replication of hepatitis B virus and induce an interferon response in human liver cells and mice

21 January 2018

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages

21 January 2018

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siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo.

21 January 2018

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Activation of anti-hepatitis C virus responses via Toll-like receptor 7.

21 January 2018

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Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

21 January 2018

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PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model

21 January 2018

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Interleukin-15 suppresses hepatitis B virus replication via IFN-β production in a C57BL/6 mouse model

21 January 2018

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IFN-gamma and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cells

21 January 2018

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The liver as a lymphoid organ

21 January 2018

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Antigen-presenting cell function in the tolerogenic liver environment.

21 January 2018

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

21 January 2018

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Hepatic T cells and liver tolerance

21 January 2018

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IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo

21 January 2018

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PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver.

21 January 2018

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TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence

21 January 2018

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5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

21 January 2018

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Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection

21 January 2018

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Rational design of immunostimulatory siRNAs.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/HEP.26339

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23 November 2017

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