PcrV antibody-antibiotic combination improves survival in Pseudomonas aeruginosa-infected mice (Q43472217)

23 November 2017

PcrV antibody-antibiotic combination improves survival in Pseudomonas aeruginosa-infected mice (English)

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23 November 2017

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Pseudomonas aeruginosa

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Y Song

1

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23 November 2017

M Baer

2

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23 November 2017

R Srinivasan

3

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23 November 2017

J Lima

4

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23 November 2017

G Yarranton

5

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23 November 2017

C Bebbington

6

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23 November 2017

S V Lynch

7

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23 November 2017

21 December 2011

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European Journal of Clinical Microbiology & Infectious Diseases

23 November 2017

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23 November 2017

31

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23 November 2017

8

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23 November 2017

1837-1845

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https://scigraph.springernature.com/pub.10.1007/s10096-011-1509-2

23 November 2017

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The type III secretion system tip complex and translocon.

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Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections

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ExoU is a potent intracellular phospholipase

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ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system

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Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo

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Exoenzyme T of Pseudomonas aeruginosa elicits cytotoxicity without interfering with Ras signal transduction

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Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments

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Function and molecular architecture of the Yersinia injectisome tip complex

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The V antigen of Pseudomonas aeruginosa is required for assembly of the functional PopB/PopD translocation pore in host cell membranes

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Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV.

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Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury

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Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model

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Therapeutic administration of anti-PcrV F(ab')(2) in sepsis associated with Pseudomonas aeruginosa.

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The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity

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Pilicides-small molecules targeting bacterial virulence.

21 January 2018

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Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria.

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An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity

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A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates.

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Role of persisters and small-colony variants in antibiotic resistance of planktonic and biofilm-associated Staphylococcus aureus: an in vitro study.

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Effect of anti-PcrV antibody in a murine chronic airway Pseudomonas aeruginosa infection model

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12 December 2020

Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S

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12 December 2020

Interruption of multiple cellular processes in HT-29 epithelial cells by Pseudomonas aeruginosa exoenzyme S.

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12 December 2020

Epidemiology and outcome of Pseudomonas aeruginosa bacteremia, with special emphasis on the influence of antibiotic treatment. Analysis of 189 episodes

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12 December 2020

Effects of differential expression of the 49-kilodalton exoenzyme S by Pseudomonas aeruginosa on cultured eukaryotic cells

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12 December 2020

Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: prevalence, incidence, risk factors, and outcomes

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12 December 2020

Passive anti-PcrV treatment protects burned mice against Pseudomonas aeruginosa challenge

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12 December 2020

10.1007/S10096-011-1509-2

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DOI

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Dimensions Publication ID

23 November 2017

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