Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells. (Q43484431)

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5 November 2019

title

Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells (English)

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5 November 2019

3

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5 November 2019

author name string

C D Surh

1

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5 November 2019

D S Lee

2

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5 November 2019

L Karlsson

4

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5 November 2019

J Sprent

5

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5 November 2019

language of work or name

English

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publication date

1 August 1997

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5 November 2019

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5 November 2019

volume

7

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5 November 2019

issue

2

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5 November 2019

page(s)

209-219

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Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

5 November 2019

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T cell receptor antagonist peptides induce positive selection

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Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

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The repertoire of T cells shaped by a single MHC/peptide ligand.

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Positive selection of thymocytes

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T cell tolerance by clonal elimination in the thymus

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

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Upregulation of surface markers on dying thymocytes

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

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Comparison of peptides bound to spleen and thymus class II.

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H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

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Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

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Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

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Positive selection of T cells induced by viral delivery of neopeptides to the thymus

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7 January 2021

Permissive recognition during positive selection.

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7 January 2021

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

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7 January 2021

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

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Are MHC-bound peptides a nuisance for positive selection?

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9285406%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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