Melatonin suppresses iron-induced neurodegeneration in rat brain (Q43502844)

24 November 2017

Melatonin suppresses iron-induced neurodegeneration in rat brain (English)

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24 November 2017

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Lin AM

1

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PubMed ID

10802221

24 November 2017

Ho LT

series ordinal

2

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24 November 2017

1 March 2000

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Free Radical Biology and Medicine

24 November 2017

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24 November 2017

28

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24 November 2017

6

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24 November 2017

904-911

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Free-radical toxicity and antioxidant medications in Parkinson's disease

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The causes of Parkinson's disease are being unraveled and rational neuroprotective therapy is close to reality

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Neuroprotective therapies.

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Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site.

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7 January 2021

Oxidative stress and antioxidant therapy in Parkinson's disease

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7 January 2021

Oxidative damage in the central nervous system: protection by melatonin

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Melatonin: a peroxyl radical scavenger more effective than vitamin E.

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7 January 2021

Melatonin inhibits iron-induced epileptic discharges in rats by suppressing peroxidation.

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7 January 2021

Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro

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7 January 2021

Melatonin and vitamin E limit nitric oxide-induced lipid peroxidation in rat brain homogenates.

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Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions.

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7 January 2021

Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole.

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7 January 2021

Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin

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7 January 2021

Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress.

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7 January 2021

Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide.

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7 January 2021

Neuroprotection by melatonin from kainate-induced excitotoxicity in rats

1 reference

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7 January 2021

The antioxidant melatonin reduces cortical neuronal death after intrastriatal injection of kainate in the rat.

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7 January 2021

Protective effect of melatonin in a model of traumatic brain injury in mice.

1 reference

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7 January 2021

Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats.

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7 January 2021

Oxygen toxicity, oxygen radicals, transition metals and disease

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7 January 2021

An introduction to the free radical hypothesis in Parkinson's disease

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Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress

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7 January 2021

Oxidants, antioxidants, and the degenerative diseases of aging

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7 January 2021

Parkinson's disease: a disorder due to nigral glutathione deficiency?

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7 January 2021

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

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7 January 2021

Human aging brain disorders: role of antioxidant enzymes.

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7 January 2021

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

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7 January 2021

Does oxidative stress participate in nerve cell death in Parkinson's disease?

1 reference

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7 January 2021

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

1 reference

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7 January 2021

In vivo lipid peroxidation in rat brain following intracortical Fe2+ injection.

1 reference

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7 January 2021

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

1 reference

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7 January 2021

Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

1 reference

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7 January 2021

S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo

1 reference

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7 January 2021

Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress.

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7 January 2021

Striatal dopamine dynamics are altered following an intranigral infusion of iron in adult rats.

1 reference

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7 January 2021

Ferrous-citrate complex and nigral degeneration: evidence for free-radical formation and lipid peroxidation.

1 reference

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7 January 2021

Measurement of fluorescent lipid peroxidation products in biological systems and tissues.

1 reference

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7 January 2021

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

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7 January 2021

Regional lipid peroxidation in rat brain in vitro: possible role of endogenous iron.

1 reference

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7 January 2021

Melatonin increases gene expression for antioxidant enzymes in rat brain cortex.

1 reference

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7 January 2021

Melatonin stimulates brain glutathione peroxidase activity.

1 reference

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7 January 2021

The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead, and zinc: an adsorptive voltammetric study

1 reference

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7 January 2021

10.1016/S0891-5849(00)00169-6

Identifiers

DOI

1 reference

24 November 2017

1 reference

PubMed ID

10802221