Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads (Q43508070)

24 November 2017

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads (English)

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24 November 2017

nodal receptor complex

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Gene Ontology release 2020-05-02

Kumar A

1

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24 November 2017

Novoselov V

2

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24 November 2017

Celeste AJ

3

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24 November 2017

Wolfman NM

4

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24 November 2017

ten Dijke P

5

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24 November 2017

Kuehn MR

6

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24 November 2017

language of work or name

English

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publication date

1 January 2001

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

1

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24 November 2017

656-661

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TGF-beta signal transduction

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Nodal signalling in vertebrate development.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M004649200

Smads: transcriptional activators of TGF-beta responses

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M004649200

Regulation of Smad activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Smad2 role in mesoderm formation, left-right patterning and craniofacial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Insertional mutation of a gene involved in growth regulation of the early mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Activin signalling has a necessary function in Xenopus early development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

A role of the cryptic gene in the correct establishment of the left-right axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Crystallization and preliminary X-ray analysis of recombinant human transforming growth factor beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Smad3 mutant mice develop metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

The EGF-CFC protein one-eyed pinhead is essential for nodal signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Expression of transforming-growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004649200

21 January 2018

Identifiers

DOI

10.1074/JBC.M004649200

1 reference

24 November 2017

1 reference