Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor (Q43515303)

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English	Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor	scientific article

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scholarly article

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Europe PubMed Central

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24 November 2017

Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor (English)

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Europe PubMed Central

PubMed publication ID

24 November 2017

author name string

Junquero D

1

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24 November 2017

Oms P

2

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24 November 2017

Carilla-Durand E

3

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24 November 2017

Autin J

4

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24 November 2017

Tarayre J

5

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24 November 2017

Degryse A

6

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24 November 2017

Patoiseau J

7

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24 November 2017

Colpaert FC

8

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24 November 2017

Delhon A

9

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24 November 2017

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publication date

1 January 2001

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24 November 2017

Biochemical Pharmacology

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24 November 2017

61

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24 November 2017

1

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24 November 2017

97-108

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24 November 2017

Current and future treatment of hyperlipidemia: the role of statins

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Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents

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Activation of the alternative pathway of complement by microcrystalline cholesterol

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Subacute toxicity of a novel inhibitor of acyl-CoA: cholesterol acyltransferase in beagle dogs.

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Acyl-coenzyme A: cholesterol acyltransferase assay: silica gel column separation of reaction products

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A simplification of the protein assay method of Lowry et al. which is more generally applicable

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TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters

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Bile salt-dependent, neutral cholesteryl ester hydrolase of rat liver: possible relationship with pancreatic cholesteryl ester hydrolase

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Determination of Lecithin: Cholesterol Acyltransfer in Human Blood Plasma

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In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver

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Demonstration of a direct effect on hepatic acyl CoA: cholesterol acyl transferase (ACAT) activity by an orally administered enzyme inhibitor in the hamster

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7 January 2021

Regulation and immunolocalization of acyl-coenzyme A: cholesterol acyltransferase in mammalian cells as studied with specific antibodies

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7 January 2021

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

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7 January 2021

Morphogenesis of a zone-specific adrenocortical cytotoxicity in guinea pigs administered PD 132301-2, an inhibitor of acyl-CoA:cholesterol acyltransferase

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7 January 2021

Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and morphometric evaluation

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7 January 2021

The relationship between the degree of dietary-induced hypercholesterolemia in the rabbit and atherosclerotic lesion formation

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7 January 2021

Cholesterol-fed and casein-fed rabbit models of atherosclerosis. Part 2: Differing morphological severity of atherogenesis despite matched plasma cholesterol levels.

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7 January 2021

Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster

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7 January 2021

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and hepatic apolipoprotein B secretion.

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Relation of plaque lipid composition and morphology to the stability of human aortic plaques.

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Cholesterol Esterification and Hydrolysis in the Adrenal Cortex - The Role of Acyl-CoA:Cholesterol Acyltransferase

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7 January 2021

Potent, selective, and systemically-available inhibitors of acyl-coenzyme A:cholesterol acyl transferase (ACAT).

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7 January 2021

Effect of the acyl-CoA:cholesterol acyltransferase inhibitor DuP 128 on cholesterol absorption and serum cholesterol in humans

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7 January 2021

Low-density lipoproteins of the postprandial state induce cellular cholesteryl ester accumulation in macrophages.

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7 January 2021

ACAT inhibition decreases LDL cholesterol in rabbits fed a cholesterol-free diet. Marked changes in LDL cholesterol without changes in LDL receptor mRNA abundance

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7 January 2021

Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet

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7 January 2021

Anti-atherosclerotic effect of E5324, an inhibitor of acyl-CoA:cholesterol acyltransferase, in Watanabe heritable hyperlipidemic rabbits

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7 January 2021

Use of transgenic mice in lipoprotein metabolism and atherosclerosis research.

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Difference between normal and WHHL rabbits in susceptibility to the adrenal toxicity of an acyl-CoA:cholesterol acyltransferase inhibitor, FR145237

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7 January 2021

Acyl-coenzyme A:cholesteryl acyltransferase 2.

1 reference

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7 January 2021

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

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7 January 2021

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

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The NCI-H295 cell line: a pluripotent model for human adrenocortical studies

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Identifiers

10.1016/S0006-2952(00)00523-2

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Europe PubMed Central

PubMed publication ID

24 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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