Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons (Q43540612)

24 November 2017

Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons (English)

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24 November 2017

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Allen JW

1

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24 November 2017

Shanker G

series ordinal

2

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24 November 2017

Aschner M

series ordinal

3

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24 November 2017

language of work or name

English

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publication date

1 March 2001

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24 November 2017

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24 November 2017

894

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24 November 2017

1

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24 November 2017

131-140

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Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis

24 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Methylmercury alters glutamate transport in astrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Transport of cystine and cysteine in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Inhibition of amino acid transport and protein synthesis by HgCl2 and methylmercury in astrocytes: selectivity and reversibility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

In vitro evidence for the role of glutamate in the CNS toxicity of mercury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Expression of gamma-glutamyl transpeptidase in mouse perivascular astrocytes and in a protoplasmic-like astroglial cell clone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Neurotoxic effects of mercury—A review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

The effects of glutathione glycoside in methyl mercury poisoning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

7 January 2021

Excitotoxic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

A role for gamma-glutamyl transpeptidase in the transport of cystine into human endothelial cells: relationship to intracellular glutathione

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Oxidative stress, glutamate, and neurodegenerative disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Astrocytes as mediators of methylmercury neurotoxicity: effects on D-aspartate and serotonin uptake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Mechanisms of use of extracellular glutathione by lung epithelial cells and pulmonary artery endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Kinetic and pharmacological analysis of L-[35S]cystine transport into rat brain synaptosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Dissociation of neonatal rat brain by dispase for preparation of primary astrocyte cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

gamma-Glutamyl transpeptidase, a glutathionase: its expression and function in carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Deferoxamine inhibits methyl mercury-induced increases in reactive oxygen species formation in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Neural circuits in the 21st century: synaptic networks of neurons and glia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Glutamine Synthetase: Glial Localization in Brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Reduced methylmercury accumulation in a methylmercury-resistant rat pheochromocytoma PC12 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

The role of -SH groups in methylmercuric chloride-induced D-aspartate and rubidium release from rat primary astrocyte cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Biosynthesis and maintenance of GSH in primary astrocyte cultures: role of L-cystine and ascorbate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

The gamma-glutamyl cycle: a possible transport system for amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Maintenance of neuronal glutathione by glial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

The activation of metabotropic glutamate receptors protects nerve cells from oxidative stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Induction of cystine transport via system x-c and maintenance of intracellular glutathione levels in pancreatic acinar and islet cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Glutamate and glutamine metabolism and compartmentation in astrocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

A fluorometric assay for γ-glutamyl transpeptidase: Demonstration of enzymatic activity in cultured cells of neural origin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Glutamate transport and metabolism in astrocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Increased vulnerability of neurones and glial cells to low concentrations of methylmercury in a prooxidant situation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Oxidative mechanisms in the toxicity of metal ions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

A role for gamma-glutamyl transpeptidase and the amino acid transport system xc- in cystine transport by a human pancreatic duct cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Astrocytes provide cysteine to neurons by releasing glutathione

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Gamma-glutamyl transpeptidase does not act as a cystine transporter in brain microvessels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Role of nitric oxide in the cerebellar degeneration during methylmercury intoxication.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

Regulatory role of astrocytes for neuronal biosynthesis and homeostasis of glutamate and GABA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2901988-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-8993(01)01988-6

1 reference

24 November 2017

1 reference