CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells (Q43562885)

24 November 2017

CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells (English)

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24 November 2017

8

Stephen P Schoenberger

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Matthias G von Herrath

9

object named as

Matthias G von Herrath

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24 November 2017

Dirk Homann

1

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24 November 2017

Angelika Jahreis

2

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24 November 2017

Tom Wolfe

3

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24 November 2017

Anna Hughes

4

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24 November 2017

Bryan Coon

5

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24 November 2017

Marianne J B van Stipdonk

6

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24 November 2017

Kiley R Prilliman

7

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24 November 2017

language of work or name

English

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publication date

1 March 2002

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24 November 2017

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24 November 2017

16

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24 November 2017

403-415

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24 November 2017

3

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CD8+ T Cells Rapidly Acquire NK1.1 and NK Cell-Associated Molecules Upon Stimulation In Vitro and In Vivo

24 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Functional expression of B7/BB1 on activated T lymphocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Dendritic cells and the control of immunity

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https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Interferons alpha and beta as immune regulators--a new look

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Suppression of murine thyroiditis via blockade of the CD40-CD40L interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Human natural killer (NK) cells present staphylococcal enterotoxin B (SEB) to T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Treatment of murine lupus with CTLA4Ig

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Dendritic cells acquire antigens from live cells for cross-presentation to CTL.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

The immunoregulatory effects of NK cells: the role of TGF-beta and implications for autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Rat spleen dendritic cells express natural killer cell receptor protein 1 (NKR-P1) and have cytotoxic activity to select targets via a Ca2+-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

The development, maturation, and turnover rate of mouse spleen dendritic cell populations.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Regulation of adaptive immunity by natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Rapid Peptide Turnover and Inefficient Presentation of Exogenous Antigen Critically Limit the Activation of Self-Reactive CTL by Dendritic Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Induction of immunologic tolerance for transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Phenotypic and functional characterization of CD11c+ dendritic cell population in mouse Peyer's patches

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Models of T cell anergy: is there a common molecular mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

A subset of cytolytic dendritic cells in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Cytotoxic activity of human dendritic cells is differentially regulated by double-stranded RNA and CD40 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Natural killer (NK) cell response to virus infections in mice with severe combined immunodeficiency. The stimulation of NK cells and the NK cell-dependent control of virus infections occur independently of T and B cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900290-X

7 January 2021

10.1016/S1074-7613(02)00290-X

Identifiers

DOI

1 reference

24 November 2017

1 reference