Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. (Q43572865)

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6 November 2019

title

Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation (English)

1 reference

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amyotrophic lateral sclerosis

6 November 2019

main subject

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author

Ole A. Andreassen

1

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6 November 2019

Alpaslan Dedeoglu

3

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6 November 2019

Kimberly Ferrante

4

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6 November 2019

Rima Kaddurah-Daouk

6

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6 November 2019

7

M F Beal

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6 November 2019

author name string

B G Jenkins

2

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6 November 2019

M B Bogdanov

5

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6 November 2019

language of work or name

English

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publication date

1 April 2001

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Journal of Neurochemistry

6 November 2019

published in

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6 November 2019

volume

77

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6 November 2019

page(s)

383-390

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6 November 2019

issue

2

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Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase

6 November 2019

cites work

1 reference

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Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis

21 January 2018

1 reference

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Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

21 January 2018

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

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Glutamate uptake is decreased tardively in the spinal cord of FALS mice.

21 January 2018

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Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

21 January 2018

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

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Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls

21 January 2018

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Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

21 January 2018

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4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

21 January 2018

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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

21 January 2018

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ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

21 January 2018

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Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis

21 January 2018

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The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia

21 January 2018

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Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain

21 January 2018

1 reference

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Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain

21 January 2018

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

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Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

21 January 2018

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Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

21 January 2018

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Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

21 January 2018

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Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

21 January 2018

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

21 January 2018

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Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production.

21 January 2018

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Mild kainate toxicity produces selective motoneuron death with marked activation of CA(2+)-permeable AMPA/kainate receptors.

21 January 2018

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Peroxynitrite inhibits glutamate transporter subtypes.

21 January 2018

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SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

21 January 2018

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Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis.

21 January 2018

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An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

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