Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat. (Q43581358)

24 November 2017

Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat. (English)

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24 November 2017

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5

Siesjö BK

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24 November 2017

Yoshimoto T

1

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24 November 2017

Uchino H

series ordinal

2

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24 November 2017

He QP

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3

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24 November 2017

Li PA

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4

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24 November 2017

language of work or name

English

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publication date

1 April 2001

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24 November 2017

11

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based on heuristic

inferred from page(s)

published in

Brain Research

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24 November 2017

899

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24 November 2017

1-2

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24 November 2017

148-158

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Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

24 November 2017

1 reference

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Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

7 January 2021

1 reference

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High level calcineurin activity predisposes neuronal cells to apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

7 January 2021

1 reference

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Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

7 January 2021

1 reference

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

7 January 2021

1 reference

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

7 January 2021

1 reference

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Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis?

7 January 2021

1 reference

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

7 January 2021

1 reference

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Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

7 January 2021

1 reference

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N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia

7 January 2021

1 reference

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Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

7 January 2021

1 reference

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

7 January 2021

1 reference

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Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarisation and the permeability transition but not by cytochrome c release

7 January 2021

1 reference

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Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia.

7 January 2021

1 reference

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The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

7 January 2021

1 reference

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Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion

7 January 2021

1 reference

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The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat.

7 January 2021

1 reference

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Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

7 January 2021

1 reference

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Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases

7 January 2021

1 reference

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In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier

7 January 2021

1 reference

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Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Transport of cyclosporin A across the brain capillary endothelial cell monolayer by P-glycoprotein

7 January 2021

1 reference

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Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

7 January 2021

1 reference

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Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Interaction of cyclosporin derivatives with the ATPase activity of human P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902220-X

10.1016/S0006-8993(01)02220-X

7 January 2021

Identifiers

DOI

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24 November 2017

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