RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase (Q43583328)

24 November 2017

title

RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase (English)

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24 November 2017

Jeffrey A Knauf

1

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24 November 2017

Hiroaki Kuroda

series ordinal

2

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24 November 2017

Saswata Basu

series ordinal

3

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24 November 2017

James A Fagin

series ordinal

4

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24 November 2017

language of work or name

English

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publication date

1 July 2003

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24 November 2017

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24 November 2017

volume

22

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24 November 2017

issue

28

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24 November 2017

page(s)

4406-4412

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Grb2 binding to the different isoforms of Ret tyrosine kinase.

24 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Identification of Shc docking site on Ret tyrosine kinase

21 January 2018

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Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

21 January 2018

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The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Characterization of the upstream enhancer of the rat sodium/iodide symporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.

21 January 2018

1 reference

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Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain

21 January 2018

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Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression

21 January 2018

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Multiple mechanisms of interference between transformation and differentiation in thyroid cells

21 January 2018

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One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes

21 January 2018

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RAS oncogene activation induces proliferation in normal human thyroid epithelial cells without loss of differentiation

21 January 2018

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

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Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells

21 January 2018

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Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

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Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

21 January 2018

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Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities

21 January 2018

1 reference

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Hormonal control of the transcription factor Pax8 and its role in the regulation of thyroglobulin gene expression in thyroid cells

21 January 2018

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Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells

21 January 2018

1 reference

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

21 January 2018

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A general and fast method to generate multiple site directed mutations

21 January 2018

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Molecular events involved in differentiation of thyroid follicular cells.

21 January 2018

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Multiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1

21 January 2018

1 reference

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The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

The Ret Receptor Protein Tyrosine Kinase Associates with the SH2-containing Adapter Protein Grb10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7

21 January 2018

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Genetic markers in thyroid neoplasia

21 January 2018

1 reference

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Gene rearrangement and Chernobyl related thyroid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Characterization of a thyroid-specific and cyclic adenosine monophosphate-responsive enhancer far upstream from the human sodium iodide symporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Iodide symporter gene expression in normal and transformed rat thyroid cells.

21 January 2018

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Oncogenes and thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

Oncogenic rearrangements of the ret proto-oncogene in thyroid tumors induced after exposure to ionizing radiation

21 January 2018

1 reference

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7 January 2021

Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

Preferential induction of RET/PTC1 rearrangement by X-ray irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

Continued expression of a tissue specific activated oncogene in the early steps of radiation-induced human thyroid carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

Molecular mechanisms of RET activation in human cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206602

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206602

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Dimensions Publication ID

24 November 2017

1018892721

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