Cytosolic PrP Induces Apoptosis of Cell by Disrupting Microtubule Assembly (Q43595653)

25 November 2017

title

Cytosolic PrP induces apoptosis of cell by disrupting microtubule assembly (English)

1 reference

25 November 2017

Cytosolic PrP Induces Apoptosis of Cell by Disrupting Microtubule Assembly (English)

1 reference

https://api.crossref.org/works/10.1007/S12031-010-9443-9

12 July 2024

8

Qi Shi

1 reference

25 November 2017

10

Xiao-Ping Dong

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25 November 2017

Xiao-Li Li

1

1 reference

25 November 2017

Gui-Rong Wang

2

1 reference

25 November 2017

Yuan-Yuan Jing

3

1 reference

25 November 2017

Ming-Ming Pan

4

1 reference

25 November 2017

Chen-Fang Dong

5

1 reference

25 November 2017

Rui-Min Zhou

6

1 reference

25 November 2017

Zhao-Yun Wang

7

1 reference

25 November 2017

Chen Gao

9

1 reference

25 November 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20838930

12 July 2024

publication date

14 September 2010

1 reference

full work available at URL

25 November 2017

http://link.springer.com/content/pdf/10.1007/s12031-010-9443-9.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S12031-010-9443-9

http://link.springer.com/article/10.1007/s12031-010-9443-9/fulltext.html

12 July 2024

1 reference

https://api.crossref.org/works/10.1007/S12031-010-9443-9

http://link.springer.com/content/pdf/10.1007/s12031-010-9443-9

12 July 2024

1 reference

https://api.crossref.org/works/10.1007/S12031-010-9443-9

Journal of Molecular Neuroscience

12 July 2024

published in

1 reference

25 November 2017

volume

43

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25 November 2017

issue

3

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25 November 2017

page(s)

316-325

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Prions: health scare and biological challenge.

25 November 2017

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Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.

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The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro

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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

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Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

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The role of disulfide bridge in the folding and stability of the recombinant human prion protein

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Microtubules, microtubule-interfering agents and apoptosis.

21 January 2018

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Direct interaction between prion protein and tubulin

21 January 2018

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Prion protein region 23-32 interacts with tubulin and inhibits microtubule assembly

21 January 2018

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21 January 2018

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Protection from cytosolic prion protein toxicity by modulation of protein translocation

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A novel mutation (G114V) in the prion protein gene in a family with inherited prion disease

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Scrapie prion protein contains a phosphatidylinositol glycolipid

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Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.

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Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons

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Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol

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The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity

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Human tau protein forms complex with PrP and some GSS- and fCJD-related PrP mutants possess stronger binding activities with tau in vitro

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Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway

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Changes of tau profiles in brains of the hamsters infected with scrapie strains 263 K or 139 A possibly associated with the alteration of phosphate kinases

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The Cellular Prion Protein Colocalizes with the Dystroglycan Complex in the Brain

21 January 2018

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Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

21 January 2018

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12 December 2020

Cytosolic prion protein in neurons.

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12 December 2020

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12 December 2020

Prion protein inhibits microtubule assembly by inducing tubulin oligomerization

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12 December 2020

Human prion protein mutants with deleted and inserted octarepeats undergo different pathways to trigger cell apoptosis

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12 December 2020

Identifiers

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Dimensions Publication ID

25 November 2017

1016632147

0 references

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