A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function (Q43597080)

25 November 2017

A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function (English)

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25 November 2017

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D A Parasrampuria

1

1 reference

PubMed ID

11336351

25 November 2017

M V Lantz

series ordinal

2

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PubMed ID

11336351

25 November 2017

L Z Benet

series ordinal

3

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25 November 2017

1 January 2001

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25 November 2017

Pharmaceutical Research

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25 November 2017

18

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25 November 2017

1

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25 November 2017

39-44

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Multidrug transporters from bacteria to man: similarities in structure and function

25 November 2017

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12 December 2020

Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells

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12 December 2020

How does P-glycoprotein recognize its substrates?

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12 December 2020

Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

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12 December 2020

Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein

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12 December 2020

Grapefruit juice activates P-glycoprotein-mediated drug transport

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay

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12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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12 December 2020

The mechanism of ATP-dependent multidrug transport by P-glycoprotein.

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12 December 2020

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

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12 December 2020

Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans

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12 December 2020

Carrier mechanisms involved in the transepithelial transport of bis(POM)-PMEA and its metabolites across Caco-2 monolayers

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12 December 2020

Analysis of ion transport perturbations caused by hu MDR 1 protein overexpression

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12 December 2020

Net secretion of furosemide is subject to indomethacin inhibition, as observed in Caco-2 monolayers and excised rat jejunum

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12 December 2020

Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.

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12 December 2020

Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.

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12 December 2020

Calcein accumulation as a fluorometric functional assay of the multidrug transporter

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12 December 2020

Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes.

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12 December 2020

Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4+ and CD8+ T cells from patients with human immunodeficiency virus type 1 infection

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12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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12 December 2020

Identifiers

DOI

10.1023/A:1011070509191

1 reference

25 November 2017

1 reference

PubMed ID

11336351