Nitrogen inversion barriers affect the N-oxidation of tertiary alkylamines by cytochromes P450. (Q43598166)

25 November 2017

Nitrogen inversion barriers affect the N-oxidation of tertiary alkylamines by cytochromes P450. (English)

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25 November 2017

1

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25 November 2017

Lars Olsen

6

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author name string

Martin S Jørgensen

2

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25 November 2017

Thomas A Jacobsen

3

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25 November 2017

Anne-Marie Jacobsen

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25 November 2017

Kim G Madsen

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25 November 2017

language of work or name

English

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publication date

28 November 2012

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Angewandte Chemie International Edition

25 November 2017

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volume

52

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25 November 2017

3

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25 November 2017

993-997

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Cytochrome P450s and other enzymes in drug metabolism and toxicity

25 November 2017

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https://api.crossref.org/works/10.1002%2FANIE.201206207

Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201206207

Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201206207

Sulfoxide, Sulfur, and Nitrogen Oxidation and Dealkylation by Cytochrome P450

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RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes

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A comprehensive listing of bioactivation pathways of organic functional groups

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Human Liver Microsomal Metabolism and DNA Adduct Formation of the Tumorigenic Pyrrolizidine Alkaloid, Riddelliine

21 January 2018

1 reference

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Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201206207

Oxidizing species in the mechanism of cytochrome P450.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201206207

Evidence for the involvement of cytochrome P-450 in tiaramide N-oxide reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201206207

Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201206207

Anilinic N-oxides support cytochrome P450-mediated N-dealkylation through hydrogen-atom transfer

21 January 2018

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The SMARTCyp cytochrome P450 metabolism prediction server

21 January 2018

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SMARTCyp: A 2D Method for Prediction of Cytochrome P450-Mediated Drug Metabolism

21 January 2018

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Ligand-Based Site of Metabolism Prediction for Cytochrome P450 2D6.

21 January 2018

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Fast Prediction of Cytochrome P450 Mediated Drug Metabolism

21 January 2018

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Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine

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Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver

21 January 2018

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The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes

21 January 2018

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Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron

21 January 2018

1 reference

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Oxidation of tertiary amines by cytochrome p450-kinetic isotope effect as a spin-state reactivity probe

21 January 2018

1 reference

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Kinetic isotope effect is a sensitive probe of spin state reactivity in C-H hydroxylation of N,N-dimethylaniline by cytochrome P450.

21 January 2018

1 reference

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Regulatory mechanisms in the activation of nitrogenous compounds by mammalian cytochrome P-450 isozymes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANIE.201206207

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release_rgqdknewu5fzrjc5v2rtdcxz3a

25 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/rgqdknewu5fzrjc5v2rtdcxz3a

mapped directly with Wikidata item

24 November 2022

based on heuristic

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