The predicted beta12-beta13 loop is important for inhibition of PP2Acalpha by the antitumor drug fostriecin (Q43628470)

25 November 2017

title

The predicted beta12-beta13 loop is important for inhibition of PP2Acalpha by the antitumor drug fostriecin (English)

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25 November 2017

Evans DR

1

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25 November 2017

Simon JA

series ordinal

2

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25 November 2017

language of work or name

English

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publication date

1 June 2001

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25 November 2017

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25 November 2017

volume

498

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25 November 2017

issue

1

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25 November 2017

page(s)

110-115

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Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

25 November 2017

cites work

1 reference

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

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Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A.

21 January 2018

1 reference

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Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902448-6

Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate

21 January 2018

1 reference

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A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.

21 January 2018

1 reference

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Inhibitor-1 interaction domain that mediates the inhibition of protein phosphatase-1.

21 January 2018

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Mutagenesis of the catalytic subunit of rabbit muscle protein phosphatase-1.

21 January 2018

1 reference

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Importance of the β12-β13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

21 January 2018

1 reference

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In vitro activity of the novel antitumor antibiotic fostriecin (CI-920) in a human tumor cloning assay

21 January 2018

1 reference

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Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters

21 January 2018

1 reference

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A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A

21 January 2018

1 reference

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Tyrosine-272 is involved in the inhibition of protein phosphatase-1 by multiple toxins

21 January 2018

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Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms

21 January 2018

1 reference

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Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae

21 January 2018

1 reference

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Purification of type 1 protein (serine/threonine) phosphatases by microcystin-Sepharose affinity chromatography

21 January 2018

1 reference

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Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I. Taxonomy, fermentation and biological properties.

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(01)02448-6

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25 November 2017

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