The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors (Q43628479)

25 November 2017

title

The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors (English)

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25 November 2017

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2

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25 November 2017

Mankouri HW

1

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25 November 2017

language of work or name

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1 August 2001

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Mechanisms of Ageing and Development

25 November 2017

published in

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25 November 2017

volume

122

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25 November 2017

issue

11

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25 November 2017

page(s)

1107-1120

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Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein

25 November 2017

cites work

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7 January 2021

Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae.

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7 January 2021

Defending genome integrity during DNA replication: a proposed role for RecQ family helicases

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7 January 2021

The Bloom's syndrome gene product is homologous to RecQ helicases

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7 January 2021

The gene responsible for Werner syndrome may be a cell division "counting" gene

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7 January 2021

Mutator phenotype of Werner syndrome is characterized by extensive deletions

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7 January 2021

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

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7 January 2021

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

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7 January 2021

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

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7 January 2021

The Werner syndrome protein is a DNA helicase

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https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900253-6

7 January 2021

Bloom's syndrome gene suppresses premature ageing caused by Sgs1 deficiency in yeast

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7 January 2021

The Bloom's syndrome gene product is a 3'-5' DNA helicase

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7 January 2021

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

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7 January 2021

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

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7 January 2021

DNA topoisomerase poisons as antitumor drugs

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7 January 2021

Human homologues of yeast helicase

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7 January 2021

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

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7 January 2021

Sgs1 helicase activity is required for mitotic but apparently not for meiotic functions

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7 January 2021

WRN mutations in Werner syndrome

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7 January 2021

Werner's syndrome lymphoblastoid cells are hypersensitive to topoisomerase II inhibitors in the G2 phase of the cell cycle

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7 January 2021

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

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7 January 2021

Importance of the Sgs1 helicase activity in DNA repair of Saccharomyces cerevisiae

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7 January 2021

The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases

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7 January 2021

Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.

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7 January 2021

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

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7 January 2021

Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta

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7 January 2021

Extrachromosomal rDNA circles--a cause of aging in yeast

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7 January 2021

Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants

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7 January 2021

A screen for dominant negative mutants of SEC18 reveals a role for the AAA protein consensus sequence in ATP hydrolysis

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7 January 2021

Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation

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7 January 2021

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

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7 January 2021

Positional cloning of the Werner's syndrome gene

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7 January 2021

10.1016/S0047-6374(01)00253-6

Identifiers

DOI

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25 November 2017

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