Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation (Q43651488)

25 November 2017

Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation (English)

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25 November 2017

reactive oxygen species

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Fonck C

1

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PubMed ID

11423095

25 November 2017

Baudry M

series ordinal

2

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PubMed ID

11423095

25 November 2017

language of work or name

English

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publication date

1 June 2001

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25 November 2017

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25 November 2017

905

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25 November 2017

199-206

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25 November 2017

1-2

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Rasagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation

25 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Enhanced hydroxyl radical generation by 2'-methyl analog of MPTP: suppression by clorgyline and deprenyl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

MPTP fails to induce lipid peroxidation in vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Inhibition of Biogenic Amine Uptake by Hydrogen Peroxide: A Mechanism for Toxic Effects of 6-Hydroxydopamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

MPTP toxicity in rat striatal slices: dopamine uptake alteration does not appear to be related to lipid peroxidation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Expression of dopamine transporter at the tips of growing neurites of PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Changes of energy metabolism induced by 1-methyl-4-phenylpyridinium (MPP+)-related compounds in rat pheochromocytoma PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Lipid peroxidation in rat brain cortical slices as measured by the thiobarbituric acid test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Mechanisms of action of 6-hydroxydopamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Transgenic murine dopaminergic neurons expressing human Cu/Zn superoxide dismutase exhibit increased density in culture, but no resistance to methylphenylpyridinium-induced degeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC 12 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

Oxidation of 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine, a 1-amino analog of MPTP, by type A and B monoamine oxidase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2902551-3

10.1016/S0006-8993(01)02551-3

7 January 2021

Identifiers

DOI

1 reference

25 November 2017

1 reference

PubMed ID

11423095