Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. (Q43662802)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

E J Morris

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

E Keramaris

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

H J Rideout

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

R S Slack

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

N J Dyson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

L Stefanis

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

D S Park

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 July 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

5017-5026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

Pathobiology of ischaemic stroke: an integrated view

9 November 2019

cites work

1 reference

12 December 2020

Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.

1 reference

12 December 2020

Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

1 reference

12 December 2020

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

12 December 2020

Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.

1 reference

12 December 2020

Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1.

1 reference

12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

12 December 2020

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

1 reference

12 December 2020

Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle

1 reference

12 December 2020

Apoptosis in neurodegenerative disorders

1 reference

12 December 2020

Retinoblastoma protein partners

1 reference

12 December 2020

MR of cis-platinum-induced optic neuritis.

1 reference

12 December 2020

Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinosides and topoisomerase II inhibitors in the presence of NGF

1 reference

12 December 2020

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

12 December 2020

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

12 December 2020

Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons.

1 reference

12 December 2020

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

1 reference

12 December 2020

p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

1 reference

12 December 2020

Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.

1 reference

12 December 2020

The transcription factor E2F1 modulates apoptosis of neurons

1 reference

12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

12 December 2020

Etoposide induces programmed death in neurons cultured from the fetal rat central nervous system.

1 reference

12 December 2020

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

1 reference

12 December 2020

Rb protein down-regulates the stress-activated signals through inhibiting c-Jun N-terminal kinase/stress-activated protein kinase.

1 reference

12 December 2020

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

1 reference

12 December 2020

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

1 reference

12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

12 December 2020

Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

1 reference

12 December 2020

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

1 reference

12 December 2020

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

1 reference

12 December 2020

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

1 reference

12 December 2020

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

12 December 2020

Cell-cycle control and its watchman.

1 reference

12 December 2020

p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation

1 reference

12 December 2020

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

12 December 2020

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

12 December 2020

Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death.

1 reference

12 December 2020

Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

1 reference

12 December 2020

Role of NF-κB in p53-mediated programmed cell death

1 reference

12 December 2020

Filamentous degeneration of neurons. A possible feature of cytosine arabinoside neurotoxicity

1 reference

12 December 2020

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

12 December 2020

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

12 December 2020

Bax involvement in p53-mediated neuronal cell death

1 reference

12 December 2020

The retinoblastoma gene product (Rb) induces binding of a conformationally inactive nuclear factor-kappaB.

1 reference

12 December 2020

Cell death during development of the nervous system

1 reference

12 December 2020

p14ARF links the tumour suppressors RB and p53.

1 reference

12 December 2020

Functional interaction between retinoblastoma protein and stress-activated protein kinase in multiple myeloma cells

1 reference

12 December 2020

Role of the p53-homologue p73 in E2F1-induced apoptosis

1 reference

12 December 2020

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

1 reference

12 December 2020

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

12 December 2020

Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?

1 reference

12 December 2020

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

12 December 2020

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

1 reference

12 December 2020

Induction of cyclin B and H1 kinase activity in apoptotic PC12 cells

1 reference

12 December 2020

Cytarabine and neurologic toxicity

1 reference

12 December 2020

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

1 reference

12 December 2020

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

12 December 2020

Cerebellar degeneration caused by high-dose cytosine arabinoside: a clinicopathological study

1 reference

12 December 2020

Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction

1 reference

12 December 2020

Cyclin-dependent kinases as a therapeutic target for stroke.

1 reference

12 December 2020

10.1523/JNEUROSCI.21-14-05017.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438577%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference