Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. (Q43677197)

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28 December 2019

title

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia (English)

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28 December 2019

3

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28 December 2019

author name string

Silvia Amadesi

1

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28 December 2019

Jingjiang Nie

2

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28 December 2019

Graeme S Cottrell

4

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28 December 2019

Eileen F Grady

5

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28 December 2019

Marcello Trevisani

6

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28 December 2019

Chiara Manni

7

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28 December 2019

Pierangelo Geppetti

8

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28 December 2019

James A McRoberts

9

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Helena Ennes

10

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28 December 2019

John B Davis

11

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28 December 2019

Emeran A Mayer

12

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28 December 2019

Nigel W Bunnett

13

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language of work or name

English

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publication date

1 May 2004

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28 December 2019

published in

Journal of Neuroscience

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28 December 2019

volume

24

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28 December 2019

page(s)

4300-4312

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28 December 2019

issue

18

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Ion channels gated by heat

28 December 2019

cites work

1 reference

12 December 2020

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

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12 December 2020

Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin

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12 December 2020

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

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A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice

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Cathepsin G activates protease-activated receptor-4 in human platelets

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Purification and characterization of a trypsin-like serine proteinase from rat brain slices that degrades laminin and type IV collagen and stimulates protease-activated receptor-2

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12 December 2020

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

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12 December 2020

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

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12 December 2020

Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways

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12 December 2020

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

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12 December 2020

Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C.

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12 December 2020

Loose ligation of the rat sciatic nerve is accompanied by changes in the subcellular content of protein kinase C beta II and gamma in the spinal dorsal horn

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12 December 2020

Extrapancreatic trypsin-2 cleaves proteinase-activated receptor-2.

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12 December 2020

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

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12 December 2020

Induction of vanilloid receptor channel activity by protein kinase C

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12 December 2020

Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats

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12 December 2020

Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia

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12 December 2020

The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection

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12 December 2020

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

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12 December 2020

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

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12 December 2020

Hyperalgesia induced by peripheral inflammation is mediated by protein kinase C betaII isozyme in the rat spinal cord

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12 December 2020

Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

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12 December 2020

Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism

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12 December 2020

The proteinase-activated receptor 2 is involved in nociception.

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12 December 2020

Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons

1 reference

12 December 2020

Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli

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12 December 2020

Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues

1 reference

12 December 2020

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

1 reference

12 December 2020

Capsazepine partially inhibits neurally mediated gastric mucus secretion following activation of protease-activated receptor 2.

1 reference

12 December 2020

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

1 reference

12 December 2020

PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia.

1 reference

12 December 2020

Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways

1 reference

12 December 2020

Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia.

1 reference

12 December 2020

Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes

1 reference

12 December 2020

Capsazepine inhibits thermal hyperalgesia but not nociception triggered by protease-activated receptor-2 in rats

1 reference

12 December 2020

Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia.

1 reference

12 December 2020

Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine

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12 December 2020

Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2

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12 December 2020

Expression of calcitonin gene-related peptide, substance P and protein kinase C in cultured dorsal root ganglion neurons following chronic exposure to mu, delta and kappa opiates

1 reference

12 December 2020

Voltage-dependent priming of rat vanilloid receptor: effects of agonist and protein kinase C activation

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12 December 2020

Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

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12 December 2020

Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency

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12 December 2020

Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability

1 reference

12 December 2020

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

1 reference

12 December 2020

Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway

1 reference

12 December 2020

Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats

1 reference

12 December 2020

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

1 reference

12 December 2020

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1 reference

12 December 2020

Enhancement by prostaglandin E2 of bradykinin activation of embryonic rat sensory neurones

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12 December 2020

Molecular cloning of a potential proteinase activated receptor

1 reference

12 December 2020

Mechanisms of desensitization and resensitization of proteinase-activated receptor-2.

1 reference

12 December 2020

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

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12 December 2020

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

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12 December 2020

Protease-activated receptor 3 is a second thrombin receptor in humans

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12 December 2020

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

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12 December 2020

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

1 reference

12 December 2020

Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma

1 reference

12 December 2020

Nociceptin inhibits T-type Ca2+ channel current in rat sensory neurons by a G-protein-independent mechanism

1 reference

12 December 2020

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1 reference

12 December 2020

A dual thrombin receptor system for platelet activation

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12 December 2020

The cloned capsaicin receptor integrates multiple pain-producing stimuli

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12 December 2020

Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro.

1 reference

12 December 2020

10.1523/JNEUROSCI.5679-03.2004

Identifiers

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