Delayed effects of tamoxifen in hepatocarcinogenesis-resistant Fischer 344 rats as compared with susceptible strains (Q43696019)

25 November 2017

Delayed effects of tamoxifen in hepatocarcinogenesis-resistant Fischer 344 rats as compared with susceptible strains (English)

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25 November 2017

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Stanley LA

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25 November 2017

Carthew P

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25 November 2017

Davies R

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25 November 2017

Higginson F

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25 November 2017

Martin E

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25 November 2017

Styles JA

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25 November 2017

language of work or name

English

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publication date

1 September 2001

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25 November 2017

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25 November 2017

171

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1

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25 November 2017

27-35

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Does tamoxifen cause cancer in humans?

25 November 2017

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Thickened endometrium caused by tamoxifen returns to normal following tamoxifen cessation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Modulation of endometrial transforming growth factor beta (TGFbeta) by tamoxifen

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Malignant endometrial polyps in postmenopausal breast cancer tamoxifen-treated patients

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Endometrial histopathology in 700 patients treated with tamoxifen for breast cancer

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Uterine carcinosarcomas in patients receiving tamoxifen. A report of 19 cases

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Tamoxifen in liver disease: potential exacerbation of hepatic dysfunction

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Hepatocellular carcinoma after long-term tamoxifen therapy

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Interspecies differences in cancer susceptibility and toxicity

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

DNA damage as assessed by 32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Tamoxifen induces hepatocellular carcinoma in rat liver: a 1-year study with two antiestrogens

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

The role of cell death and cell proliferation in the promotion of rat liver tumours by tamoxifen

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Sulfation of alpha-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

The metabolic activation of tamoxifen and alpha-hydroxytamoxifen to DNA- binding species in rat hepatocytes proceeds via sulphation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

N-Demethylation accompanies α-hydroxylation in the metabolic activation of tamoxifen in rat liver cells

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Alpha-hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Evaluation of tamoxifen and alpha-hydroxytamoxifen 32P-post-labelled DNA adducts by the development of a novel automated on-line solid-phase extraction HPLC method.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Determination of DNA damage in F344 rats induced by geometric isomers of tamoxifen and analogues

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

DNA adduct formation by tamoxifen and structurally-related compounds in rat liver

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Further characterization of the DNA adducts formed in rat liver after the administration of tamoxifen, N-desmethyltamoxifen or N, N-didesmethyltamoxifen

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Site-specific tamoxifen-DNA adduct formation: lack of correlation with mutational ability in Escherichia coli

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Tamoxifen induces G:C-->T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5'-CpG-3' dinucleotide sequences as found in the lacI transgene.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Comparison of the DNA adducts formed by tamoxifen and 4-hydroxytamoxifen in vivo.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Tamoxifen and toremifene in breast cancer: comparison of safety and efficacy

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Uterotrophic effects of tamoxifen, toremifene, and raloxifene do not predict endometrial cell proliferation in the ovariectomized CD1 mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Structure-activity relationships for triphenylethylene antiestrogens on hepatic phase-I and phase-II enzyme expression

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Comparison of the effects of tamoxifen and toremifene on rat hepatocarcinogenesis

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Genotoxicity studies with the antiestrogen toremifene.

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Effects of ethinyl estradiol and tamoxifen on liver DNA turnover and new synthesis and appearance of gamma glutamyl transpeptidase-positive foci in female rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Progression: the terminal stage in carcinogenesis

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Clastogenic and aneugenic effects of tamoxifen and some of its analogues in hepatocytes from dosed rats and in human lymphoblastoid cells transfected with human P450 cDNAs (MCL-5 cells).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900564-X

7 January 2021

10.1016/S0304-3835(01)00564-X

Identifiers

DOI

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25 November 2017

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