Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems (Q43712808)

26 November 2017

Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems (English)

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26 November 2017

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26 November 2017

Magnus Ingelman-Sundberg

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object named as

Ingelman-Sundberg M

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Pelkonen O

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Myllynen P

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Taavitsainen P

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Watts P

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Lake BG

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Price RJ

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Renwick AB

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Gómez-Lechón MJ

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Castell JV

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26 November 2017

Hidestrand M

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Guillouzo A

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Corcos L

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Goldfarb PS

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Lewis DF

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language of work or name

English

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publication date

1 June 2001

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26 November 2017

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31

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321-343

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6

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A simple and sensitive assay of 7-ethoxycoumarin deethylation

26 November 2017

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Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

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Inhibition and induction of human cytochrome P450 (CYP) enzymes

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Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

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Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse

21 January 2018

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Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

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Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5.

21 January 2018

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Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices

21 January 2018

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Immunochemical detection of human liver cytochrome P450 forms related to phenobarbital-inducible forms in the mouse

21 January 2018

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Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

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Culture of precision-cut liver slices: effect of some peroxisome proliferators

21 January 2018

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A new carbamazepine metabolite in uraemic filtrate

21 January 2018

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Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans

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Cytochrome b5 as electron donor to rabbit liver cytochrome P-450LM2 in reconstituted phospholipid vesicles

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Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

21 January 2018

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High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

21 January 2018

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A new instrument for the rapid preparation of tissue slices

21 January 2018

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Induction of CYP3A isoforms in cultured precision-cut human liver slices

21 January 2018

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3,3'-Diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices

21 January 2018

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Quantitative determination of dextromethorphan and three metabolites in urine by reverse-phase high-performance liquid chromatography

21 January 2018

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Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

21 January 2018

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Improved detection and determination of carbamazepine and oxcarbazepine and their metabolites by high-performance liquid chromatography

21 January 2018

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Use of in vitro human metabolism studies in drug development. An industrial perspective

21 January 2018

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Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

21 January 2018

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Single-dose kinetics and metabolism of carbamazepine-10,11-epoxide

21 January 2018

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Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

21 January 2018

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10.1080/00498250110055479

21 January 2018

Identifiers

DOI

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26 November 2017

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