Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer (Q43721974)

26 November 2017

Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer (English)

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26 November 2017

1

Darwin J Operario

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26 November 2017

Mini Balakrishnan

2

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26 November 2017

Robert A Bambara

series ordinal

3

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26 November 2017

Baek Kim

series ordinal

4

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26 November 2017

language of work or name

English

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publication date

21 August 2006

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Journal of Biological Chemistry

26 November 2017

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26 November 2017

281

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26 November 2017

43

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26 November 2017

32113-32121

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A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase

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DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

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Escherichia coli DNA polymerase I (Klenow fragment) uses a hydrogen-bonding fork from Arg668 to the primer terminus and incoming deoxynucleotide triphosphate to catalyze DNA replication.

21 January 2018

1 reference

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

1 reference

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Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate

21 January 2018

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Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity

21 January 2018

1 reference

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A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis

21 January 2018

1 reference

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Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

21 January 2018

1 reference

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Mechanistic Understanding of an Altered Fidelity Simian Immunodeficiency Virus Reverse Transcriptase Mutation, V148I, Identified in a Pig-tailed Macaque

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Mechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptases

21 January 2018

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Modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dNTP concentrations

21 January 2018

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Pausing during reverse transcription increases the rate of retroviral recombination

21 January 2018

1 reference

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DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase

21 January 2018

1 reference

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Mechanistic analysis of pause site-dependent and -independent recombinogenic strand transfer from structurally diverse regions of the HIV genome.

21 January 2018

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HIV-1 sequence variation: drift, shift, and attenuation

21 January 2018

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Retroviral Recombination and Reverse Transcription

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Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure.

21 January 2018

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HIV-1 acquires resistance to two classes of antiviral drugs through homologous recombination

21 January 2018

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Genetic selection in Escherichia coli for active human immunodeficiency virus reverse transcriptase mutants

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Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation

21 January 2018

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First large scale chemical synthesis of the 72 amino acid HIV-1 nucleocapsid protein NCp7 in an active form.

21 January 2018

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Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases

21 January 2018

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Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli

21 January 2018

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Template dimerization promotes an acceptor invasion-induced transfer mechanism during human immunodeficiency virus type 1 minus-strand synthesis

21 January 2018

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The kissing hairpin sequence promotes recombination within the HIV-I 5' leader region.

21 January 2018

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Acceptor RNA cleavage profile supports an invasion mechanism for HIV-1 minus strand transfer

21 January 2018

1 reference

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Identification of a preferred region for recombination and mutation in HIV-1 gag.

21 January 2018

1 reference

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Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency

21 January 2018

1 reference

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Physiological concentrations of purines and pyrimidines

21 January 2018

1 reference

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Comparison of the genetic recombination rates of human immunodeficiency virus type 1 in macrophages and T cells

21 January 2018

1 reference

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Dynamics of HIV-1 recombination in its natural target cells

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21 January 2018

Identifiers

DOI

10.1074/JBC.M604665200

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26 November 2017

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