Functional modulation of the glucocorticoid receptor and suppression of NF-kappaB-dependent transcription by ursodeoxycholic acid (Q43750966)

26 November 2017

Functional modulation of the glucocorticoid receptor and suppression of NF-kappaB-dependent transcription by ursodeoxycholic acid (English)

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26 November 2017

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Miura T

1

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26 November 2017

Ouchida R

2

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26 November 2017

Yoshikawa N

3

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26 November 2017

Okamoto K

4

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26 November 2017

Makino Y

5

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26 November 2017

Nakamura T

6

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26 November 2017

Morimoto C

7

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26 November 2017

Makino I

8

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26 November 2017

Tanaka H

9

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26 November 2017

language of work or name

English

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publication date

27 September 2001

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Journal of Biological Chemistry

26 November 2017

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26 November 2017

276

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26 November 2017

50

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26 November 2017

47371-47378

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From a choleretic to an immunomodulator: historical review of ursodeoxycholic acid as a medicament.

26 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Primary biliary cirrhosis: an orchestrated immune response against epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

The immunosuppressive effect of ursodeoxycholic acid: a comparative in vitro study on human peripheral blood mononuclear cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Biochemistry, molecular biology, and physiology of the glucocorticoid receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Nuclear receptors, coactivators and chromatin: new approaches, new insights

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

The structure of the nuclear hormone receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Transcriptional cross-talk, the second mode of steroid hormone receptor action.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Regulation of inducible gene expression by the transcription factor NF-kappaB.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-kappa B p65-mediated transcription as a coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

High-performance affinity beads for identifying drug receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Various glucocorticoids differ in their ability to induce gene expression, apoptosis and to repress NF-kappaB-dependent transcription

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Thioredoxin: a redox-regulating cellular cofactor for glucocorticoid hormone action. Cross talk between endocrine control of stress response and cellular antioxidant defense system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Identification of a nuclear receptor for bile acids

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

FXR, a bile acid receptor and biological sensor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Separable features of the ligand-binding domain determine the differential subcellular localization and ligand-binding specificity of glucocorticoid receptor and progesterone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

A ligand binding domain mutation in the mouse glucocorticoid receptor functionally links chromatin remodeling and transcription initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Conformational change in the human glucocorticoid receptor induced by ligand binding is altered by mutation of isoleucine 747 by a threonine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

Alteration of the glucocorticoid receptor subcellular localization by non steroidal compounds

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107098200

Serum concentrations of ursodeoxycholic acid in portal venous and systemic venous blood of fasting humans as determined by isotope dilution-mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107098200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107098200

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26 November 2017

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