Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease. (Q43761427)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301904%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease (English)

1 reference

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22 January 2020

0 references

2

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22 January 2020

author name string

Ning Sun

series ordinal

1

1 reference

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22 January 2020

Zhanar Abil

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301904%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Huimin Zhao

series ordinal

4

1 reference

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22 January 2020

publication date

3 February 2012

1 reference

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22 January 2020

number of pages

9

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based on heuristic

inferred from page(s)

published in

Molecular BioSystems

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22 January 2020

volume

8

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22 January 2020

issue

4

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22 January 2020

page(s)

1255-1263

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Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review

22 January 2020

cites work

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Sickle cell disease: old discoveries, new concepts, and future promise

21 January 2018

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Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells

21 January 2018

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Correction of sickle cell disease in transgenic mouse models by gene therapy

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Gene therapy death prompts review of adenovirus vector

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Correction of the sickle cell mutation in embryonic stem cells

21 January 2018

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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 January 2018

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Homologous recombination in mammalian cells

21 January 2018

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Gene conversion tracts from double-strand break repair in mammalian cells

21 January 2018

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Zinc-finger nucleases: the next generation emerges

21 January 2018

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Genome editing with engineered zinc finger nucleases

21 January 2018

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Progress and prospects: zinc-finger nucleases as gene therapy agents

21 January 2018

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Unexpected failure rates for modular assembly of engineered zinc fingers

21 January 2018

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Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications

21 January 2018

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Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

21 January 2018

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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

21 January 2018

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Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

21 January 2018

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De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

21 January 2018

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A TALE nuclease architecture for efficient genome editing

21 January 2018

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 January 2018

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Targeted genome editing across species using ZFNs and TALENs

21 January 2018

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A simple cipher governs DNA recognition by TAL effectors

21 January 2018

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Breaking the code of DNA binding specificity of TAL-type III effectors

21 January 2018

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FokI dimerization is required for DNA cleavage

21 January 2018

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A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells

21 January 2018

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Dimerization of the bacterial effector protein AvrBs3 in the plant cell cytoplasm prior to nuclear import.

21 January 2018

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A bacterial effector acts as a plant transcription factor and induces a cell size regulator

21 January 2018

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Chimeric nucleases stimulate gene targeting in human cells

21 January 2018

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

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DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

21 January 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

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Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

21 January 2018

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21 January 2018

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TAL effectors: customizable proteins for DNA targeting

21 January 2018

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High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method

21 January 2018

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