Mutations that change the position of the putative gamma-phosphate linker in the nucleotide binding domains of CFTR alter channel gating (Q43852907)

27 November 2017

title

Mutations that change the position of the putative gamma-phosphate linker in the nucleotide binding domains of CFTR alter channel gating (English)

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27 November 2017

Allan L Berger

1

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27 November 2017

Mutsuhiro Ikuma

2

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27 November 2017

John F Hunt

3

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27 November 2017

Philip J Thomas

4

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27 November 2017

Michael J Welsh

5

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

3

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27 November 2017

page(s)

2125-2131

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Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

27 November 2017

cites work

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The Cystic Fibrosis Transmembrane Conductance Regulator

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Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)

21 January 2018

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Structural and functional similarities between the nucleotide-binding domains of CFTR and GTP-binding proteins

21 January 2018

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Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis.

21 January 2018

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Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme

21 January 2018

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Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis

21 January 2018

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Crystal structure of the ATP-binding subunit of an ABC transporter

21 January 2018

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Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

21 January 2018

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Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter

21 January 2018

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Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

21 January 2018

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The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

21 January 2018

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Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

21 January 2018

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Redox reagents and divalent cations alter the kinetics of cystic fibrosis transmembrane conductance regulator channel gating

21 January 2018

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Phosphate stimulates CFTR Cl- channels

21 January 2018

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Regulation of CFTR Cl- channel gating by ADP and ATP analogues

21 January 2018

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Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation

21 January 2018

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Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two different nucleotide binding sites

21 January 2018

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Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis

21 January 2018

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Pyrophosphate stimulates wild-type and mutant cystic fibrosis transmembrane conductance regulator Cl- channels

21 January 2018

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Differential interactions of nucleotides at the two nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator

21 January 2018

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Assignment of the gene encoding the catalytic subunit C beta of cAMP-dependent protein kinase to the p36 band on chromosome 1

21 January 2018

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Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein

21 January 2018

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Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide

21 January 2018

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Walker A lysine mutations of TAP1 and TAP2 interfere with peptide translocation but not peptide binding.

21 January 2018

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Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

21 January 2018

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RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

21 January 2018

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Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2

21 January 2018

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Three novel mutations in the cystic fibrosis gene detected by chemical cleavage: analysis of variant splicing and a nonsense mutation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109539200

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27 November 2017

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