ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation (Q43854028)

27 November 2017

ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation (English)

1 reference

27 November 2017

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1 reference

Uffe B Olsen

1

1 reference

27 November 2017

Christina T Eltorp

2

1 reference

27 November 2017

Bente K Ingvardsen

3

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27 November 2017

Tine K Jørgensen

4

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27 November 2017

Jens A Lundbaek

5

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27 November 2017

Christian Thomsen

6

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27 November 2017

Anker J Hansen

7

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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European Journal of Pharmacology

27 November 2017

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27 November 2017

435

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27 November 2017

1

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27 November 2017

43-57

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Protein kinase C inhibitors decrease hyperalgesia and C-fiber hyperexcitability in the streptozotocin-diabetic rat.

27 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Histamine-induced edema in the rat paw--effect of capsaicin denervation and a CGRP receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Evidence of a key-role for histamine from mast cells in the analgesic effect of clomipramine in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Effects of cutaneous histamine application in patients with sympathetic reflex dystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Diphenhydramine potentiates narcotic but not endogenous opioid analgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Heterogeneity of histamine H1-receptors: species variations in [3H]mepyramine binding of brain membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The inflammatory reaction induced by formalin in the rat paw.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The effects of substance P on histamine and 5-hydroxytryptamine release in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Effect of neonatal treatment with capsaicin on carrageenan-induced paw oedema in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Effects of antidepressant drugs on different receptors in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The binding of [3H]mepyramine to histamine H1 receptors in guinea-pig brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The tail-flick and formalin tests in rodents: changes in skin temperature as a confounding factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Possible mechanism of c-fos expression in trigeminal nucleus caudalis following cortical spreading depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Studies on the vascular permeability induced by intrathecal substance P and bradykinin in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Superficial dorsal horn neurons identified by intracutaneous histamine: chemonociceptive responses and modulation by morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Gene expression of histamine H1 receptor in guinea pig primary sensory neurons: a relationship between H1 receptor mRNA-expressing neurons and peptidergic neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Antinociception following 1,3,-di-o-tolylguanidine, a selective sigma receptor ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

1,3-Di-o-tolylguanidine (DTG) differentially affects acute and tonic formalin pain: antagonism by rimcazole

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

H1-receptor-mediated excitation and facilitation of the heat response by histamine in canine visceral polymodal receptors studied in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Mast cells synthesize, store, and release nerve growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The sensory-efferent function of capsaicin-sensitive sensory neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Evidence for hypernociception induction following histamine H1 receptor activation in rodents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Role of histamine H(1) receptor in pain perception: a study of the receptor gene knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The modulation of inflammatory oedema by calcitonin gene-related peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Opiate and histamine H1 receptors are present on some substance P-containing dorsal root ganglion cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Localization of opiate and histamine H1-receptors in the primate sensory ganglia and spinal cord.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Antidepressant-induced analgesia in chronic non-malignant pain: a meta-analysis of 39 placebo-controlled studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Studies on cutaneous vascular permeability in the rat: Increases caused by histamine and histamine-like agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The distribution of histamine H1-receptors in the rat brain: An autoradiographic study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Histamine-immunoreactive nerve fibers in the mammalian spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Regional distribution of calcitonin gene-related peptide-, substance P-, cholecystokinin-, Met5-enkephalin-, and dynorphin A (1-8)-like materials in the spinal cord and dorsal root ganglia of adult rats: effects of dorsal rhizotomy and neonatal caps

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

In vivo occupation of cerebral histamine H1-receptors evaluated with 3H-mepyramine may predict sedative properties of psychotropic drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Antihistamines as analgesics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Do dorsal root reflexes augment peripheral inflammation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Clinical efficacy of antihistaminics as analgesics.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

The capsaicin test in mice for evaluating tachykinin antagonists in the spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Specific C-receptors for itch in human skin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

[3H]7-OH-DPAT labels both dopamine D3 receptors and sigma sites in the bovine caudate nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

p-chlorophenylalanine-reversible reduction of sigma binding sites by chronic imipramine treatment in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Neurotrophins and hyperalgesia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Psychophysical Studies of the Itch Sensation and Itchy Skin (“Alloknesis”) Produced by Intracutaneous Injection of Histamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Regulation of the human histamine H1 receptor stably expressed in Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

3HDoxepin interactions with histamine H1-receptors and other sites in guinea pig and rat brain homogenates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Neurogenic and tissue-mediated components of formalin-induced edema: evidence for supraspinal regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Transport mechanism of an H1-antagonist at the blood-brain barrier: transport mechanism of mepyramine using the carotid injection technique.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

[3H]-(+)-pentazocine binding to sigma recognition sites in human cerebellum.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

Mast cells in the nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901556-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-2999(01)01556-4

1 reference

27 November 2017

1 reference