Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase. (Q43860404)

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6 December 2019

title

Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase (English)

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6 December 2019

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Ramón Hurtado-Guerrero

1

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6 December 2019

Javier Pena-Diaz

2

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6 December 2019

Luis Miguel Ruiz-Pérez

4

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Dolores Gonzalez-Pacanowska

6 December 2019

5

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6 December 2019

author name string

Andrea Montalvetti

3

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6 December 2019

language of work or name

English

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publication date

1 January 2002

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6 December 2019

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6 December 2019

volume

510

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6 December 2019

page(s)

141-144

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6 December 2019

issue

3

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Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies

6 December 2019

cites work

1 reference

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Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis

21 January 2018

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Protein engineering of the HMG-CoA reductase of Pseudomonas mevalonii. Construction of mutant enzymes whose activity is regulated by phosphorylation and dephosphorylation

21 January 2018

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Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

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A soluble 3-hydroxy-3-methylglutaryl-CoA reductase in the protozoan Trypanosoma cruzi

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Use of Dimethyl Suberimidate, a Cross-Linking Reagent, in Studying the Subunit Structure of Oligomeric Proteins

21 January 2018

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Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.

21 January 2018

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Active form of Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl coenzyme A reductase.

21 January 2018

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Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase

21 January 2018

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Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity

21 January 2018

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Inhibition of Trypanosoma cruzi growth and sterol biosynthesis by lovastatin

21 January 2018

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Synergism in vitro of lovastatin and miconazole as anti-leishmanial agents

21 January 2018

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The LDL receptor and HMG-CoA reductase--two membrane molecules that regulate cholesterol homeostasis

21 January 2018

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Crystal structure of Pseudomonas mevalonii HMG-CoA reductase at 3.0 angstrom resolution

21 January 2018

1 reference

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Hydroxymethylglutaryl-CoA reductase--the rate-limiting enzyme of cholesterol biosynthesis. A report of a meeting held at Nijenrode Castle, Breukelen, The Netherlands, August 24, 1985

21 January 2018

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Slow binding inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

21 January 2018

1 reference

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10.1016/S0014-5793(01)03238-0

21 January 2018

Identifiers

DOI

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6 December 2019

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