Rap-specific GTPase activating protein follows an alternative mechanism (Q43867605)

27 November 2017

title

Rap-specific GTPase activating protein follows an alternative mechanism (English)

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27 November 2017

7

Alfred Wittinghofer

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27 November 2017

2

Oliver Daumke

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27 November 2017

Thilo Brinkmann

1

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27 November 2017

Ulrike Herbrand

3

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27 November 2017

Dorothee Kühlmann

4

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27 November 2017

Patricia Stege

5

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27 November 2017

Mohammad Reza Ahmadian

6

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27 November 2017

language of work or name

English

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publication date

25 January 2002

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

15

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27 November 2017

page(s)

12525-12531

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Rap1 signalling: adhering to new models

27 November 2017

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A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

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Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells

21 January 2018

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Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

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Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

21 January 2018

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Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk

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21 January 2018

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Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

21 January 2018

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The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

21 January 2018

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Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

21 January 2018

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Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

21 January 2018

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BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast

21 January 2018

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Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

21 January 2018

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The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

21 January 2018

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Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

21 January 2018

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21 January 2018

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Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases

21 January 2018

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Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins

21 January 2018

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

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Short-term, high-efficiency expression of transfected DNA.

21 January 2018

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Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins

21 January 2018

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Site-directed mutagenesis, fluorescence, and two-dimensional NMR studies on microenvironments of effector region aromatic residues of human c-Ha-Ras protein

21 January 2018

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Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta

21 January 2018

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Structure of ADP x AIF4(-)-stabilized nitrogenase complex and its implications for signal transduction

21 January 2018

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Ras/Rap effector specificity determined by charge reversal

21 January 2018

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Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

21 January 2018

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Interactions between Ras proteins and their effectors

21 January 2018

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The guanine nucleotide-binding switch in three dimensions

21 January 2018

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21 January 2018

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

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Structural basis for the interaction of Ras with RalGDS

21 January 2018

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Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

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Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

21 January 2018

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The Crystal Structure of rna1p

21 January 2018

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Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

21 January 2018

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Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

21 January 2018

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Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition

21 January 2018

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The conserved arginine in rho-GTPase-activating protein is essential for efficient catalysis but not for complex formation with Rho.GDP and aluminum fluoride

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109176200

Stereochemistry of the elongation factor Tu . GTP complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109176200

Is there a rate-limiting step before GTP cleavage by H-ras p21?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109176200

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structural and biochemical analysis of Ras-effector signaling via RalGDS

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109176200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109176200

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27 November 2017

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