Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP. (Q43867716)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812994%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP (English)

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6 December 2019

9

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6 December 2019

Bénédicte Manoury

1

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6 December 2019

3

Lars Fugger

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6 December 2019

author name string

Daniela Mazzeo

2

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6 December 2019

Nick Viner

4

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6 December 2019

Mary Ponsford

5

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6 December 2019

Heather Streeter

6

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6 December 2019

Graziella Mazza

7

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6 December 2019

David C Wraith

8

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6 December 2019

language of work or name

English

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publication date

14 January 2002

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6 December 2019

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6 December 2019

volume

3

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6 December 2019

issue

2

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6 December 2019

page(s)

169-174

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Immunological aspects of demyelinating diseases

6 December 2019

cites work

1 reference

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1 reference

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Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex

21 January 2018

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The human myelin basic protein gene is included within a 179-kilobase transcription unit: expression in the immune and central nervous systems

21 January 2018

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21 January 2018

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Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

21 January 2018

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An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

21 January 2018

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Control of antigen presentation by a single protease cleavage site

21 January 2018

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21 January 2018

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Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer

21 January 2018

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Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II molecules

21 January 2018

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Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein

21 January 2018

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Endogenous myelin basic protein inactivates the high avidity T cell repertoire

21 January 2018

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High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire

21 January 2018

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Negative selection during the peripheral immune response to antigen

21 January 2018

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Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins

21 January 2018

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Capture and processing of exogenous antigens for presentation on MHC molecules.

21 January 2018

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Sequence and structure determinants of the nonenzymatic deamidation of asparagine and glutamine residues in proteins

21 January 2018

1 reference

T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation

21 January 2018

1 reference

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

21 January 2018

1 reference

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

21 January 2018

1 reference

Characterization of a Recombinant Murine 18.5-kDa Myelin Basic Protein

21 January 2018

1 reference

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

21 January 2018

1 reference

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

21 January 2018

1 reference

7 January 2021

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

1 reference

7 January 2021

Intrathymic expression of genes involved in organ specific autoimmune disease

1 reference

7 January 2021

An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction

1 reference

7 January 2021

Influence of a dominant cryptic epitope on autoimmune T cell tolerance

1 reference

7 January 2021

Antigen-presenting cell activation: a link between infection and autoimmunity?

1 reference

7 January 2021

Three-dimensional structure of myelin basic protein. II. Molecular modeling and considerations of predicted structures in multiple sclerosis

1 reference

7 January 2021