Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore (Q43872516)

27 November 2017

title

Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore (English)

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27 November 2017

Ronald A Li

1

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27 November 2017

Kazuki Sato

2

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27 November 2017

Kyoko Kodama

3

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27 November 2017

Toshiyuki Kohno

4

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27 November 2017

Tian Xue

5

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27 November 2017

Gordon F Tomaselli

6

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27 November 2017

Eduardo Marbán

7

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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27 November 2017

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27 November 2017

volume

511

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27 November 2017

issue

1-3

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27 November 2017

page(s)

159-164

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Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations

27 November 2017

cites work

1 reference

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Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels

21 January 2018

1 reference

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Structure and function of voltage-sensitive ion channels

21 January 2018

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Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Pore residues critical for mu-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Charged residues between the selectivity filter and S6 segments contribute to the permeation phenotype of the sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Molecular localization of an ion-binding site within the pore of mammalian sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Extrapore residues of the S5-S6 loop of domain 2 of the voltage-gated skeletal muscle sodium channel (rSkM1) contribute to the mu-conotoxin GIIIA binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Latent specificity of molecular recognition in sodium channels engineered to discriminate between two "indistinguishable" mu-conotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Predominant interactions between mu-conotoxin Arg-13 and the skeletal muscle Na+ channel localized by mutant cycle analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Chemical shifts as a tool for structure determination

21 January 2018

1 reference

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Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Modification of Arg-13 of mu-conotoxin GIIIA with piperidinyl-Arg analogs and their relation to the inhibition of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2903316-6

Isolation and amino acid compositions of geographutoxin I and II from the marine snail Conus geographus

21 January 2018

1 reference

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Disulfide pairings in geographutoxin I, a peptide neurotoxin from Conus geographus

21 January 2018

1 reference

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Tertiary structure of conotoxin GIIIA in aqueous solution

21 January 2018

1 reference

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A novel sodium channel inhibitor from Conus geographus: purification, structure, and pharmacological properties

21 January 2018

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Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis

21 January 2018

1 reference

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10.1016/S0014-5793(01)03316-6

21 January 2018

Identifiers

DOI

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27 November 2017

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