Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis (Q43873069)

27 November 2017

Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis (English)

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27 November 2017

4

Mien-Chie Hung

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27 November 2017

Wei-Ping Lee

1

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27 November 2017

Yong Wen

series ordinal

2

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27 November 2017

Brian Varnum

series ordinal

3

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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27 November 2017

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27 November 2017

21

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27 November 2017

3

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27 November 2017

329-336

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205066

27 November 2017

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cites work

Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Adenovirus 5 E1A-mediated tumor suppression associated with E1A-mediated apoptosis in vivo.

21 January 2018

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Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype

21 January 2018

1 reference

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

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Antioncogenic effect of adenovirus E1A in human tumor cells

21 January 2018

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Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts

21 January 2018

1 reference

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Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.

21 January 2018

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Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial

21 January 2018

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

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Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

21 January 2018

1 reference

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

21 January 2018

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Transformation of NIH 3T3 cells by cotransfection with c-src and nuclear oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products

21 January 2018

1 reference

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Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene

21 January 2018

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cells

21 January 2018

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7 January 2021

Differential requirement for adenovirus type 12 E1A gene products in oncogenic transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

7 January 2021

E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

7 January 2021

The erbB2 gene as a cancer therapeutic target and the tumor- and metastasis-suppressing function of E1A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205066

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205066

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Dimensions Publication ID

27 November 2017

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