Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease (Q43903756)

27 November 2017

Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease (English)

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27 November 2017

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D E Undlien

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E Thorsby

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B P C Koeleman

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B A Lie

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F Dudbridge

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R R P de Vries

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F Cucca

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B O Roep

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M J Giphart

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J A Todd

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1 August 2004

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381-388

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https://scigraph.springernature.com/pub.10.1038/sj.gene.6364106

27 November 2017

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cites work

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Susceptibility to type I diabetes: HLA-DQ and DR revisited

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

HLA-DQA1 and -DQB1 alleles associated with genetic susceptibility to IDDM in a black population

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

An increased risk of insulin-dependent diabetes mellitus (IDDM) among HLA-DR4,DQw8/DRw8,DQw4 heterozygotes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Invited anniversary review: HLA associated diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer

21 January 2018

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Molecular basis for HLA-DQ associations with IDDM.

21 January 2018

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The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

HLA-DR and the development of rheumatoid arthritis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Reevaluation of the importance of polymorphic HLA class II alleles and amino acids in the susceptibility of individuals of different populations to type I diabetes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Likelihoods and TDT for the case-parents design.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

An extended transmission/disequilibrium test (TDT) for multi-allele marker loci.

21 January 2018

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Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and –DRB1

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

HLA class II associations with Type 1 diabetes mellitus: a multivariate approach

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Statistical aspects of measuring the strength of associations between HLA antigens and diseases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Transcomplementation of HLA DQA1-DQB1 in DR3/DR4 and DR3/DR9 Heterozygotes and IDDM in Taiwanese Families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Intracellular competition for component chains determines class II MHC cell surface phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

A new predictive model for insulin-dependent diabetes mellitus susceptibility based on combinations of molecular HLA-DRB1 and HLA-DQB1 pockets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

On estimating HLA/disease association with application to a study of aplastic anemia

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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364106

7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6364106

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27 November 2017

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