Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice (Q43904357)

27 November 2017

Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice (English)

1 reference

27 November 2017

Hyemyung Seo

1

1 reference

27 November 2017

Andrew W Ferree

series ordinal

2

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27 November 2017

Ole Isacson

series ordinal

3

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27 November 2017

language of work or name

English

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publication date

1 February 2002

1 reference

European Journal of Neuroscience

27 November 2017

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27 November 2017

15

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27 November 2017

498-506

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27 November 2017

3

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Amyloid precursor protein modulates the interaction of nerve growth factor with p75 receptor and potentiates its activation of trkA phosphorylation

27 November 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The cholinergic hypothesis of geriatric memory dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Increased beta-amyloid precursor protein mRNA in the rat cerebral cortex and hippocampus after chronic systemic atropine treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Cholinergic projections from the basal forebrain to frontal, parietal, temporal, occipital, and cingulate cortices: A combined fluorescent tracer and acetylcholinesterase analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

A synaptic model of memory: long-term potentiation in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Serum NGF levels in children and adolescents with either Williams syndrome or Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

An antibody to beta amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The localization of nerve growth factor-like immunoreactivity in the adult rat basal forebrain and hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The regulation of presenilin-1 by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor does not influence the expression of beta amyloid precursor protein mRNA in rat brain: in vivo and in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Inhibition of beta-amyloid production by activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

In situ hybridization detection of trkA mRNA in brain: distribution, colocalization with p75NGFR and up-regulation by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor pharmacology: application to the treatment of cholinergic neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor mRNA-containing cells are distributed within regions of cholinergic neurons in the rat basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor (NGF) in cerebrospinal fluid (CSF) from patients with various neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Lu 25-109, a combined m1 agonist and m2 antagonist, modulates regulated processing of the amyloid precursor protein of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Role of neurotransmission in the regulation of amyloid beta-protein precursor processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide). A potent, specific muscarinic acetylcholine receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Blocking the NGF-TrkA interaction rescues the developmental loss of LTP in the rat visual cortex: role of the cholinergic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Regulated secretion of amyloid precursor protein by TrkA receptor stimulation in rat pheochromocytoma-12 cells is mitogen activated protein kinase sensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Comparison of the effects of selective and nonselective muscarinic agonists on cognition and thermoregulation in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Can activity modulate the susceptibility of neurons to degeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Nerve growth factor signaling, neuroprotection, and neural repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Pharmacological studies on novel muscarinic agonists, 1-oxa-8-azaspiro[4.5]decane derivatives, YM796 and YM954.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Rat beta-nerve growth factor sequence and site of synthesis in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Role of the cholinergic system in the regulation of neurotrophin synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Altered NGF protein levels in different brain areas after immunolesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

Detection of increased tissue concentrations of nerve growth factor with an improved extraction procedure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01884.X

10.1046/J.0953-816X.2001.01884.X

21 January 2018

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DOI

1 reference

27 November 2017

1 reference