Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain (Q43917527)

28 November 2017

title

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain (English)

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28 November 2017

7

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28 November 2017

A Paul Mould

1

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28 November 2017

Janet A Askari

2

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28 November 2017

Stephanie Barton

3

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28 November 2017

Adam D Kline

4

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28 November 2017

Paul A McEwan

5

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28 November 2017

Susan E Craig

6

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28 November 2017

language of work or name

English

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publication date

13 March 2002

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Journal of Biological Chemistry

28 November 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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28 November 2017

volume

277

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28 November 2017

issue

22

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28 November 2017

page(s)

19800-19805

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In vivo functions of integrins: lessons from null mutations in mice

28 November 2017

cites work

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Divalent cation regulation of the function of the leukocyte integrin LFA-1

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Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

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Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

21 January 2018

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Structure. An anthropomorphic integrin

21 January 2018

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Two conformations of the integrin A-domain (I-domain): a pathway for activation?

21 January 2018

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Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

21 January 2018

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Generation of a minimal alpha5beta1 integrin-Fc fragment

21 January 2018

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Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

21 January 2018

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A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques

21 January 2018

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Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

21 January 2018

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Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

21 January 2018

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A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.

21 January 2018

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Interactions of protein antigens with antibodies

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Structural basis of collagen recognition by integrin alpha2beta1

21 January 2018

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An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain

21 January 2018

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Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

21 January 2018

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Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.

21 January 2018

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NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

21 January 2018

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Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain

21 January 2018

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21 January 2018

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Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium

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Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing.

21 January 2018

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Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state

21 January 2018

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21 January 2018

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Accurate modeling of protein conformation by automatic segment matching

21 January 2018

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Protein folding by restrained energy minimization and molecular dynamics

21 January 2018

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

21 January 2018

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Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit

21 January 2018

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Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

21 January 2018

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The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

21 January 2018

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Molecular Basis of Ligand Recognition by Integrin α5β1

21 January 2018

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Molecular Basis of Ligand Recognition by Integrin α5β1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201571200

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28 November 2017

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