Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells (Q43930852)

28 November 2017

Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells (English)

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28 November 2017

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28 November 2017

4

David J Greenblatt

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28 November 2017

2

Lisa L von Moltke

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28 November 2017

Jeanne M Fahey

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PubMed ID

17637189

28 November 2017

language of work or name

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1 July 2007

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Journal of Pharmacy and Pharmacology

28 November 2017

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28 November 2017

59

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28 November 2017

7

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28 November 2017

947-953

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Bovine brain microvessel endothelial cell monolayers as a model system for the blood-brain barrier.

28 November 2017

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https://api.crossref.org/works/10.1211%2FJPP.59.7.0006

Quantitative assessment of HIV-1 protease inhibitor interactions with drug efflux transporters in the blood-brain barrier.

21 January 2018

1 reference

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In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.

21 January 2018

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Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure

21 January 2018

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Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir

21 January 2018

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Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers

21 January 2018

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Dual protease inhibitor therapy in HIV-infected patients: pharmacologic rationale and clinical benefits

21 January 2018

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Using pharmacokinetics to optimize antiretroviral drug-drug interactions in the treatment of human immunodeficiency virus infection

21 January 2018

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Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel.

21 January 2018

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Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir

21 January 2018

1 reference

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High levels of P-glycoprotein detected in isolated brain capillaries.

21 January 2018

1 reference

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The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

21 January 2018

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Cerebrospinal fluid HIV RNA and drug levels with combination ritonavir and saquinavir.

21 January 2018

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From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

21 January 2018

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Lopinavir-Ritonavir: a new protease inhibitor

21 January 2018

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Resistance, fitness, adherence, and potency: mapping the paths to virologic failure.

21 January 2018

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Effect of widely used combinations of antiretroviral therapy on liver CYP3A4 activity in HIV-infected patients.

21 January 2018

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Ritonavir decreases the nonrenal clearance of digoxin in healthy volunteers with known MDR1 genotypes

21 January 2018

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Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture.

21 January 2018

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Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line

21 January 2018

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Rapid assessment of P-glycoprotein inhibition and induction in vitro

21 January 2018

1 reference

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Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats

21 January 2018

1 reference

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Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor.

21 January 2018

1 reference

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Increased drug delivery to the brain by P-glycoprotein inhibition

21 January 2018

1 reference

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Pharmacokinetics and safety of amprenavir and ritonavir following multiple-dose, co-administration to healthy volunteers

21 January 2018

1 reference

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Imaging P-glycoprotein transport activity at the human blood-brain barrier with positron emission tomography

21 January 2018

1 reference

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P-Glycoprotein, a gatekeeper in the blood-brain barrier

21 January 2018

1 reference

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Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.59.7.0006

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.59.7.0006

Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia

21 January 2018

1 reference

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Once-daily dosing of saquinavir and low-dose ritonavir in HIV-1-infected individuals: a pharmacokinetic pilot study

21 January 2018

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Modulation of P-glycoprotein Transport Activity in the Mouse Blood-Brain Barrier by Rifampin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1211/JPP.59.7.0006

1 reference

28 November 2017

1 reference

PubMed ID

17637189