Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei (Q43936767)

28 November 2017

Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei (English)

1 reference

multidrug resistance protein E

28 November 2017

0 references

0 references

1 reference

GeneDB

multidrug resistance protein A

5 February 2019

1 reference

6 February 2019

1 reference

3

1 reference

28 November 2017

Sanjay K Shahi

1

1 reference

PubMed ID

11918801

28 November 2017

R Luise Krauth-Siegel

series ordinal

2

1 reference

PubMed ID

11918801

28 November 2017

language of work or name

English

0 references

publication date

1 March 2002

1 reference

28 November 2017

Molecular Microbiology

1 reference

28 November 2017

43

1 reference

28 November 2017

5

1 reference

28 November 2017

1129-1138

1 reference

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

28 November 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Pharmacokinetic investigations in patients from northern Angola refractory to melarsoprol treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Characterisation of the growth and differentiation in vivo and in vitro-of bloodstream-form Trypanosoma brucei strain TREU 927.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Determination of low-molecular-weight thiols using monobromobimane fluorescent labeling and high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Metabolism and functions of trypanothione in the Kinetoplastida

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Structural, mechanistic and clinical aspects of MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Degradation of the unstable EP1 mRNA in Trypanosoma brucei involves initial destruction of the 3'-untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

The P-glycoprotein-related gene family in Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Endocytosis and secretion in trypanosomatid parasites - Tumultuous traffic in a pocket.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Gene disruption of the P-glycoprotein related gene pgpa of Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.02831.X

10.1046/J.1365-2958.2002.02831.X

21 January 2018

Identifiers

DOI

1 reference

28 November 2017

1 reference

PubMed ID

11918801