Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors (Q43938582)

28 November 2017

Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors (English)

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polycyclic aromatic hydrocarbons

28 November 2017

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Brandon D Jeffy

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PubMed ID

11921194

28 November 2017

Ryan B Chirnomas

series ordinal

2

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PubMed ID

11921194

28 November 2017

Donato F Romagnolo

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3

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28 November 2017

1 January 2002

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Environmental and Molecular Mutagenesis

28 November 2017

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28 November 2017

39

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28 November 2017

2-3

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28 November 2017

235-244

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Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents.

28 November 2017

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Tumor suppressor p53 is required to modulate BRCA1 expression

21 January 2018

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Disruption of transcription in vitro and gene expression in vivo by DNA adducts derived from a benzo[a]pyrene diol epoxide located in heterologous sequences.

21 January 2018

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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

21 January 2018

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Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells

21 January 2018

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BRCA1 mutations in primary breast and ovarian carcinomas.

21 January 2018

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

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Benzo-a-pyrene: environmental partitioning and human exposure

21 January 2018

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Estrogen does not inhibit 2,3,7, 8-tetrachlorodibenzo-p-dioxin-mediated effects in MCF-7 and Hepa 1c1c7 cells

21 January 2018

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Growth retardation and tumour inhibition by BRCA1.

21 January 2018

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Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide

21 January 2018

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Disruption of cell cycle kinetics by benzo[a]pyrene: inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G2.

21 January 2018

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Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study

21 January 2018

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DNA adduct levels associated with p53 induction and delay of MCF-7 cells in S phase after exposure to benzo[g]chrysene dihydrodiol epoxide enantiomers.

21 January 2018

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Cancer-susceptibility genes. Gatekeepers and caretakers

21 January 2018

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Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells

21 January 2018

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The formation and occurrence of polynuclear aromatic hydrocarbons associated with food

21 January 2018

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Repression of BRCA1 through a feedback loop involving p53.

21 January 2018

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Binding of the transcription factor, Sp1, to non-target sites in DNA modified by benzo[a]pyrene diol epoxide

21 January 2018

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BRCA1 expression is not directly responsive to estrogen.

21 January 2018

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The mechanism of action of alpha-naphthoflavone as an inhibitor of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression

21 January 2018

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

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Environmental factors as regulators and effectors of multistep carcinogenesis

21 January 2018

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Cellular responses to oxidative stress: the [Ah] gene battery as a paradigm

21 January 2018

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The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons

21 January 2018

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Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.

21 January 2018

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Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

21 January 2018

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Regulation of subcellular localization of the aryl hydrocarbon receptor (AhR).

21 January 2018

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Estrogen upregulation of BRCA1 expression with no effect on localization.

21 January 2018

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Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide

21 January 2018

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Molecular biology of the Ah receptor and its role in carcinogenesis

21 January 2018

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Chlorinated hydrocarbons: estrogens and antiestrogens

21 January 2018

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

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Cell cycle control, checkpoint mechanisms, and genotoxic stress

21 January 2018

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

21 January 2018

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Characterization of DNA adducts formed by the four configurationally isomeric 5,6-dimethylchrysene 1,2-dihydrodiol 3,4-epoxides.

21 January 2018

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Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

21 January 2018

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Identifying human cells capable of metabolizing various classes of carcinogens

21 January 2018

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Cellular response to DNA damage from a potent carcinogen involves stabilization of p53 without induction of p21(waf1/cip1)

21 January 2018

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Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer

21 January 2018

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Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer

21 January 2018

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Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/EM.10051

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28 November 2017

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PubMed ID

11921194