Probing the structure of the warfarin-binding site on human serum albumin using site-directed mutagenesis (Q43947460)

28 November 2017

title

Probing the structure of the warfarin-binding site on human serum albumin using site-directed mutagenesis (English)

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28 November 2017

3

Stephen Curry

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author name string

Charles E Petersen

series ordinal

1

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28 November 2017

Chung-Eun Ha

series ordinal

2

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28 November 2017

Nadhipuram V Bhagavan

series ordinal

4

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28 November 2017

language of work or name

English

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publication date

1 May 2002

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28 November 2017

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28 November 2017

volume

47

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28 November 2017

issue

2

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28 November 2017

page(s)

116-125

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describes a project that uses

28 November 2017

site-directed mutagenesis

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based on heuristic

inferred from title

cites work

Atomic structure and chemistry of human serum albumin

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Mechanism by which warfarin binds to human serum albumin. Stopped-flow kinetic experiments with two large fragments of albumin

21 January 2018

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The three recombinant domains of human serum albumin. Structural characterization and ligand binding properties

21 January 2018

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Five recombinant fragments of human serum albumin-tools for the characterization of the warfarin binding site

21 January 2018

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Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I

21 January 2018

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Conformational changes in human serum albumin around the neutral pH from circular dichroic measurements

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Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.

21 January 2018

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Isolation of albumin from whole human plasma and fractionation of albumin-depleted plasma

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Drug-protein binding: recent advances in methodology: spectroscopic techniques

21 January 2018

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Fatty acid binding to human serum albumin: new insights from crystallographic studies

21 January 2018

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Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites

21 January 2018

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Serum protein binding as a determinant of warfarin body clearance and anticoagulant effect

21 January 2018

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Antipyrine and warfarin disposition in a patient with idiopathic hypoalbuminemia

21 January 2018

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A proton nuclear magnetic resonance study of human serum albumin in the neutral pH region

21 January 2018

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Consequences of the N-B transition of albumin for the binding of warfarin in human serum

21 January 2018

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Influence of fatty acids on the binding of warfarin and phenprocoumon to human serum albumin with relation to anticoagulant therapy

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The effects of N-B transition of human serum albumin on the specific drug-binding sites

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Spectroscopic techniques in the study of protein binding. A fluorescence technique for the evaluation of the albumin binding and displacement of warfarin and warfarin-alcohol

21 January 2018

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Location and characterization of the warfarin binding site of human serum albumin. A comparative study of two large fragments

21 January 2018

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Influence of the N-B transition of human serum albumin on the structure of the warfarin-binding site.

21 January 2018

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Thermodynamics and kinetics of the neutral transition of human serum albumin, monitored by the spectral change of bound bilirubin

21 January 2018

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Expression of a human serum albumin variant with high affinity for thyroxine

21 January 2018

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Mutations in a specific human serum albumin thyroxine binding site define the structural basis of familial dysalbuminemic hyperthyroxinemia

21 January 2018

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Mutagenesis studies of thyroxine binding to human serum albumin define an important structural characteristic of subdomain 2A

21 January 2018

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Familial dysalbuminemic byperthyroxinemia may result in altered warfarin pharmacokinetics

21 January 2018

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Conformational transitions of the three recombinant domains of human serum albumin depending on pH

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PROT.10068

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28 November 2017

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