Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing (Q43962720)

28 November 2017

title

Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing (English)

1 reference

28 November 2017

1 reference

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700589

28 December 2023

author name string

Rainer Wiewrodt

1

1 reference

28 November 2017

Kunjlata Amin

2

1 reference

28 November 2017

Michael Kiefer

3

1 reference

28 November 2017

Veena Kapoor

5

1 reference

28 November 2017

Seth Force

6

1 reference

28 November 2017

Michael Chang

7

1 reference

28 November 2017

Michael Lanuti

8

1 reference

28 November 2017

Vuk P. Jovanovic

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719705

28 December 2023

Margaret E. Black

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719705

28 December 2023

Larry R. Kaiser

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719705

28 December 2023

Steven M. Albelda

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719705

28 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12719705

28 December 2023

publication date

1 May 2003

1 reference

full work available at URL

28 November 2017

https://www.nature.com/articles/7700589

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700589

https://www.nature.com/articles/7700589.pdf

28 December 2023

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700589

28 December 2023

1 reference

28 November 2017

volume

10

1 reference

28 November 2017

issue

5

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28 November 2017

page(s)

353-364

1 reference

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

28 November 2017

cites work

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Gene therapy for lung disease: hype or hope?

21 January 2018

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Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma

21 January 2018

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Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.

21 January 2018

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Gene therapy for vascular smooth muscle cell proliferation after arterial injury

21 January 2018

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Expression of a Tat-inducible herpes simplex virus-thymidine kinase gene protects acyclovir-treated CD4 cells from HIV-1 spread by conditional suicide and inhibition of reverse transcription.

21 January 2018

1 reference

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A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

21 January 2018

1 reference

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Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma.

21 January 2018

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Gene-modified PA1-STK cells home to tumor sites in patients with malignant pleural mesothelioma

21 January 2018

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A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma.

21 January 2018

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Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

21 January 2018

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A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

21 January 2018

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Adenoviral-mediated suicide gene therapy for ovarian cancer

21 January 2018

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Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer

21 January 2018

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In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial.

21 January 2018

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Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy

21 January 2018

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Targeted gene delivery by tropism-modified adenoviral vectors

21 January 2018

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Enhancement of tumor ablation by a selected HSV-1 thymidine kinase mutant

21 January 2018

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Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutant

21 January 2018

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Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants

21 January 2018

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Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy.

21 January 2018

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Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses.

21 January 2018

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Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: analysis of selected mutants in vitro

21 January 2018

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A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography

21 January 2018

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A Phase I/II Study of Herpes Simplex Virus Type 1 Thymidine Kinase “Suicide” Gene Therapy for Recurrent Glioblastoma

21 January 2018

1 reference

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The treatment of ovarian cancer with a gene modified cancer vaccine: a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700589

inferred from DOI database lookup

7 January 2021

based on heuristic

A phase I study of intralesional administration of an adenovirus vector expressing the HSV-1 thymidine kinase gene (AdV.RSV-TK) in combination with escalating doses of ganciclovir in patients with cutaneous metastatic malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700589

inferred from DOI database lookup

7 January 2021

based on heuristic

1

46

5276

FL Moolten

1986

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700589

28 December 2023

3

53

5274

SM Freeman

1993

1 reference

https://api.crossref.org/works/10.1038/SJ.CGT.7700589

28 December 2023

Identifiers

1 reference

Dimensions Publication ID

28 November 2017

1005272383

0 references

1 reference