Interaction of nateglinide with K(ATP) channel in beta-cells underlies its unique insulinotropic action (Q44000194)

28 November 2017

Interaction of nateglinide with K(ATP) channel in beta-cells underlies its unique insulinotropic action (English)

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28 November 2017

Shiling Hu

1

1 reference

PubMed ID

12020694

28 November 2017

language of work or name

English

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publication date

1 May 2002

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European Journal of Pharmacology

28 November 2017

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28 November 2017

442

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28 November 2017

1-2

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28 November 2017

163-171

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Electrophysiology of the pancreatic beta-cell

28 November 2017

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Early insulin release effectively improves glucose tolerance: studies in two rodent models of type 2 diabetes mellitus

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ATP-sensitive K+ channel modification by metabolic inhibition in isolated guinea-pig ventricular myocytes

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Clinical profile of glimepiride

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Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes

7 January 2021

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Studies on the N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanin e (A-4166)receptor in HIT T-15 cells. Displacement of [3H]glibenclamide

7 January 2021

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A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx

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The ability of a new hypoglycaemic agent, A-4166, compared to sulphonylureas, to increase cytosolic Ca2+ in pancreatic beta-cells under metabolic inhibition

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Effects of sulfonamides on a metabolite-regulated ATPi-sensitive K+ channel in rat pancreatic B-cells.

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Metabolic, ionic, and secretory response to D-glucose in islets from rats with acquired or inherited non-insulin-dependent diabetes

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Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide

7 January 2021

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Glucose-dependent and glucose-sensitizing insulinotropic effect of nateglinide: comparison to sulfonylureas and repaglinide

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Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166).

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Differential interaction of glimepiride and glibenclamide with the beta-cell sulfonylurea receptor. II. Photoaffinity labeling of a 65 kDa protein by [3H]glimepiride

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Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at beta-cells

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Adenosine triphosphate-dependent K currents activated by metabolic inhibition in rat ventricular myocytes differ from those elicited by the channel opener rilmakalim

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Pancreatic islet responsiveness to D-glucose after repeated administration of repaglinide

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Long-term effects of glibenclamide and nateglinide upon pancreatic islet function in normal and diabetic rats

7 January 2021

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Stimulation of insulin release by non-sulfonylurea hypoglycemic agents: the meglitinide family

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Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs

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Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets

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7 January 2021

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Clinical profile of the novel sulphonylurea glimepiride

7 January 2021

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Possibility of ideal blood glucose control by a new oral hypoglycemic agent, N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166), and its stimulatory effect on insulin secretion in animals.

7 January 2021

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Inhibition of K+ channels and stimulation of insulin secretion by the sulfonylurea, glimepiride, in relation to its membrane binding in pancreatic islets

7 January 2021

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The sulphonylurea receptor may be an ATP-sensitive potassium channel.

7 January 2021

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The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide

7 January 2021

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Insulin secretion from isolated rat islets induced by the novel hypoglycemic agent A-4166, a derivative of D-phenylalanine

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Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells.

7 January 2021

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10.1016/S0014-2999(02)01499-1

7 January 2021

Identifiers

DOI

1 reference

28 November 2017

1 reference

PubMed ID

12020694