New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation (Q44000727)

28 November 2017

New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation (English)

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28 November 2017

Britta M Jacobsen

1

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28 November 2017

Jennifer K Richer

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2

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28 November 2017

Stephanie A Schittone

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3

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28 November 2017

Kathryn B Horwitz

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4

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28 November 2017

language of work or name

English

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publication date

20 May 2002

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Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

31

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28 November 2017

27793-27800

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The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding

28 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Impact of progesterone receptor on cell-fate decisions during mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Hormone-dependent covalent modification and processing of human progesterone receptors in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Identification of ligands and coligands for the ecdysone-regulated gene switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Molecular chaperones activate the Drosophila ecdysone receptor, an RXR heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

EcR interacts with corepressors and harbours an autonomous silencing domain functional in both Drosophila and vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Nongenomic actions of steroid hormones in reproductive tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Regulation of progesterone receptor-mediated transcription by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Differential phosphorylation of chicken progesterone receptor in hormone-dependent and ligand-independent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

The effect of progestins on prolactin receptor gene transcription in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Transcriptional and spatiotemporal regulation of prolactin receptor mRNA and cooperativity with progesterone receptor function during ductal branch growth in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Newly expressed progesterone receptor cannot activate stable, replicated mouse mammary tumor virus templates but acquires transactivation potential upon continuous expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Characterization and mapping of the human SOX4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

Progesterone receptor isoforms expression pattern in human chordomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202584200

21 January 2018

Identifiers

DOI

10.1074/JBC.M202584200

1 reference

28 November 2017

1 reference