Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells (Q44010963)

28 November 2017

Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells (English)

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28 November 2017

5

Paul Dent

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28 November 2017

Joseph N Contessa

1

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28 November 2017

Jaime Hampton

2

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28 November 2017

Guido Lammering

3

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28 November 2017

Ross B Mikkelsen

4

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28 November 2017

Kristoffer Valerie

6

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28 November 2017

Rupert K Schmidt-Ullrich

7

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28 November 2017

language of work or name

English

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publication date

1 June 2002

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28 November 2017

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28 November 2017

21

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28 November 2017

25

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28 November 2017

4032-4041

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205500

28 November 2017

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Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells

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Regulation of Akt/PKB activation by tyrosine phosphorylation

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Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

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Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

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Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

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Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

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Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization

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Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells

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Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

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Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

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Ionizing radiation stimulates existing signal transduction pathways involving the activation of epidermal growth factor receptor and ERBB-3, and changes of intracellular calcium in A431 human squamous carcinoma cells

21 January 2018

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21 January 2018

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7 January 2021

Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation

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7 January 2021

Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor.

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7 January 2021

Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells.

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7 January 2021

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205500

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28 November 2017

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